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Showing result 1 - 5 of 9 swedish dissertations matching the above criteria.

  2. 1. Trapping Tyrosine Z : Exploring the Relay between Photochemistry and Water Oxidation in Photosystem II

    Author : Johannes Sjöholm; Stenbjörn Styring; Fikret Mamedov; A. William Rutherford; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Photosystem II; Tyrosine Z; EPR; proton-coupled electron transfer; hydrogen bond; pH;

    Abstract : Photosystem II is unique! It remains the only enzyme that can oxidize water using light as energy input. Water oxidation in photosystem II is catalyzed by the CaMn4 cluster. The electrons extracted from the CaMn4 cluster are transferred to P680+ via the tyrosine residue D1-Tyr161 (YZ). READ MORE

  4. 2. Studies of the two redox active tyrosines in Photosystem II

    Author : Nigar Ahmadova; Fikret Mamedov; Stenbjörn Styring; Robert Burnap; Uppsala universitet; []
    Keywords : Photosystem II; Tyrosine Z and D; proton-coupled electron transfer;

    Abstract : Photosystem II is a unique enzyme which catalyzes light induced water oxidation. This process is driven by highly oxidizing ensemble of four Chl molecules, PD1, PD2, ChlD1 and ChlD2 called, P680. Excitation of one of the Chls in P680 leads to the primary charge separation, P680+Pheo-. READ MORE

  5. 3. Evolutionary Analysis of the Insulin-Relaxin Gene Family from the Perspective of Gene and Genome Duplication Events

    Author : Robert Piotr Olinski; Finn Hallböök; Mike Thorndyke; Pierre Pontarotti; Uppsala universitet; []
    Keywords : Neurosciences; insulin; relaxin; insulin-like protein; gene duplication; paralogous region; Ciona intestinalis; conserved synteny; ortholog; Drosophila melanogaster; Neurovetenskap;

    Abstract : Paralogs arise by duplications and belong to families. Ten paralogs (insulin; IGF-1 and -2; INSL3-6 and 3-relaxins) constitute the human insulin-relaxin family. The aim of this study was to outline the duplications that gave rise to the vertebrate insulin-relaxin genes and the chromosomal regions in which they reside. READ MORE

  6. 4. Using Light to Regulate the Activity of RET Kinase: Design, synthesis and evaluation of photoswitchable DFG-out RET kinase inhibitors

    Author : Yongjin Xu; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; RET kinase; kinase inhibitor; DFG-out; photoparmacology; azoheteroarene; Buchwald-Hartwig coupling; quinoline; 7-azaindole;

    Abstract : Protein kinases are essential for signal transduction and regulate most cellular processes, such as metabolism, membrane transport, motility, and cell cycle. Although they play a critical role in cells and have a strong association with diseases, details of their physiologic and pathologic mechanisms remain at least partially unclear, especially the spatiotemporal dynamics of the signalling. READ MORE

  7. 5. EPR Studies of Photosystem II : Characterizing Water Oxidizing Intermediates at Cryogenic Temperatures

    Author : Kajsa G.V. Havelius; Stenbjörn Styring; Holger Dau; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Biokemi;

    Abstract : The principles of natures own light-driven water splitting catalyst, Photosystem II (PSII), can in the future inspire us to use water as electron and proton source to generate light-driven H2 production. To mimic this challenging step, it is important to understand how the enzyme system can oxidize water. READ MORE