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Showing result 1 - 5 of 21 swedish dissertations matching the above criteria.

2. 1. Modulators of UCP1-dependent thermogenesis : Glucocorticoids, diet and novel research models

   Author : Ineke H. N. Luijten; Jan Nedergaard; Onno Meijer; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; brown adipose tissue; UCP1; glucocorticoids; diet-induced thermogenesis; obesity; physiology; molekylär biovetenskap; Molecular Bioscience;

   Abstract : The activation and recruitment of brown adipose tissue (BAT) thermogenesis has been put forward as a promising strategy to reduce the disease burden of obesity and obesity-related diseases. Heat production by BAT can be attributed to the tissue-specific mitochondrial uncoupling protein 1 (UCP1). READ MORE

4. 2. Energy flow and metabolic efficiency attributed to brown adipose tissue

   Author : Gabriella von Essen; Jan Nedergaard; Susanne Klaus; Stockholms universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Brown adipose tissue; BAT; UCP1; diet-induced thermogenesis; DIT; obesity; high-fat diet; energy expenditure; fysiologi; Physiology;

   Abstract : The large capacity of brown adipose tissue (BAT) to expend energy as heat makes it an interesting potential player in weight regulation and other metabolic conditions. This is of particular interest as it has been recognized that adult humans possess BAT. READ MORE

5. 3. Genetic Analysis of Fat Metabolism in Domestic Pigs and their Wild Ancestor

   Author : Frida Berg; Leif Andersson; Maria Moller; Stefan Marklund; Sigbjörn Lien; Uppsala universitet; []
   Keywords : Genetics; Pig; Quantitative Trait Locus; Fat deposition; FAT1; Linkage map; RH map; Comparative map; Backcross; Identical by Descent mapping; Brown adipose tissue; UCP1; Genetik;

   Abstract : The domestication of the pig began about 9 000 years ago and many of the existing domestic breeds have been selected for phenotypic traits like lean meat and fast growth. Domestic pigs are phenotypically very different from the ancestral wild boar that has adapted to survive in their natural environment. READ MORE

6. 4. Regulatory Factors that Reveal Three Distinct Adipocytes : The Brown, the White and the Brite

   Author : Tomas B. Waldén; Jan Nedergaard; Stephen R. Farmer; Stockholms universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipocyte; UCP1; brite; brown; white; Hox Zic; miRNA; Physiology; Fysiologi; fysiologi; Physiology;

   Abstract : Adipose tissues have long been considered to derive from a common origin. Even the functionally different brown and white adipose tissues were generalized to share a common origin. Brown adipose tissue is a highly innervated and vascularised tissue containing multilocular and multimitochondrial brown adipocytes. READ MORE

7. 5. Brown is the new white: consequences of white adipose tissue alterations in Huntington's disease

   Author : Andy Mccourt; Biomarkörer vid hjärnsjukdomar; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Huntington’s disease; weight loss; white adipose tissue; brown adipose tissue; peripheral symptoms; R6 2 mice; UCP1; CREB1; gene expression;

   Abstract : Huntington's disease (HD) is a devastating, inherited neurodegenerative disorder caused by an expanded CAG repeat in the huntingtin gene. Peripheral symptoms, such as skeletal muscle wasting, progressive weight loss, altered body composition and endocrine disturbances exist alongside neurodegeneration. READ MORE