Search for dissertations about: "UDP-glucose"

Showing result 1 - 5 of 14 swedish dissertations containing the word UDP-glucose.

  1. 1. Gene regulation of UDP-glucose synthesis and metabolism in plants

    Author : Henrik Johansson; Pierdomenica Perata; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; antisense; Arabidopsis thaliana; carbohydrate; hybrid aspen; photosynthesis; poplar; sugar; UDP-glucose; UDP-glucose pyrophosphorylase; UDP-glucose dehydrogenase; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Abstract : Photosynthesis captures light from the sun and converts it into carbohydrates, which are utilised by almost all living organisms. The conversion between the different forms of carbohydrates is the basis to form almost all biological molecules. READ MORE

  2. 2. Plant UDP-glucose Pyrophosphorylase : Function and Regulation

    Author : Meng Meng; Leszek Kleczkowski; Javier Pozueta-Romero; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; UDP-glucose pyrophosphorylase; carbohydrate metabolism; in vivo regulation; T-DNA knockout; heterologous expression; isozyme; mutagenesis; kinetic property; oligomerization; Plant physiology; Växtfysiologi;

    Abstract : UDP-glucose pyrophosphorylase (UGPase) is an important enzyme of carbohydrate metabolism in all living organisms. The main aim of this thesis was to investigate the function and regulation of plant UGP genes as well as the UGPase proteins. READ MORE

  3. 3. Studies on the Role of UDP-Glucose Dehydrogenase in Polysaccharide Biosynthesis

    Author : Elisabet Roman; Marion Kusche-Gullberg; Hakon Leffler; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; UDP-glucose dehydrogenase; polysaccharide biosynthesis; glycosaminoglycan; A. thaliana; E. coli K5; Biokemi; Biochemistry; Biokemi; Medical and Physiological Chemistry; medicinsk och fysiologisk kemi;

    Abstract : Polysaccharides are found in all forms of life and serve diverse purposes. They are enzymatically synthesised from activated monosaccharide precursors, nucleotide sugars. One such nucleotide sugar is UDP-glucuronic acid, which is formed from UDP-glucose by the UDP-glucose dehydrogenase (UGDH) enzyme. READ MORE

  4. 4. Molecular consequences of cellular UDP-glucose deficiency

    Author : Juan Carlos Higuita V; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : A Chinese hamster fibroblast mutant cell line, deficient in UDP-glucose (UDPG), denoted as Qc, and its counterpart cell line with normalized levels of UDPG (G3), were used to determine some molecular consequences of chronic UDPG deficiency. The UDPG deficient cells lacked glycogen, had elevated rates of glucose uptake and a decreased capacity to synthesize glycogen after 120h of culture. READ MORE

  5. 5. The expression and regulation of hyaluronan synthases and their role in glycosaminoglycan synthesis

    Author : Jonas Brinck; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; hyaluronan; glycosaminoglycans; CD44; growth factors; UDP-glucose dehydrogenase; Biokemi; Biochemistry; Biokemi; Medical Biochemistry; medicinsk biokemi;

    Abstract : The glycosaminoglycan hyaluronan is an essential component of the extracellular matrix in all higher organisms, affecting cellular processes such as migration, proliferation and differentiation. Hyaluronan is synthesized by a plasma membrane bound hyaluronan synthase (HAS) which exists in three genetic isoforms. READ MORE