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Showing result 1 - 5 of 98 swedish dissertations matching the above criteria.

  2. 1. Detection and analysis of genetic alterations in normal skin and skin tumours

    Author : Åsa Sivertsson; KTH; []
    Keywords : single cell; DNA sequencing; p53; mutation; UV; BCC; pyrosequencing; malignant melanoma; N-ras;

    Abstract : The investigation of genetic alterations in cancer-relatedgenes is useful for research, prognostic and therapeuticpurposes. However, the genetic heterogeneity that often occursduring tumour progression can make correct analysischallenging. READ MORE

  4. 2. Bioanalysis using capillary electrophoresis and mass spectrometry : Applied on proteins, protein nanofibrils and polyvinyl alcohol microbubbles

    Author : Leila Josefsson; Åsa Emmer; Ulrika Nilsson; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; : amyloid; capillary electrophoresis; contrast agents; detection; human blood plasma; ionic liquids; mass spectrometry; microbubbles; polyvinyl alcohol microbubbles; protein nanofibrils; proteins; Kemi; Chemistry;

    Abstract : The sequencing of the genome of various species, including the human species, have led to increased understanding about how a protein structure is generated, and how specific structures are related to the proteins’ functionality. In paper I and II of this thesis, the folding of proteins in vitro to form hierarchical nanostructures, which in vivo often have a pathological effect, have been studied. READ MORE

  5. 3. Sample Preparation of Organic Compounds in Environmental Analysis using Liquid Membrane Extraction

    Author : Luke Chimuka; Kemiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; reverse phase liquid chromatography; octanol-water partition coefficients; phenolic compounds; s-triazines; supported-liquid membrane extraction; environmental analysis; UV detection; Analytical chemistry; Analytisk kemi;

    Abstract : This thesis demonstrates the potential of the liquid membrane extraction technique as an alternative method for the analysis of trace ionisable organic compounds in the environment. Liquid membrane based extraction methods for the analysis of s-triazine herbicides and phenolic compounds were developed. READ MORE

  6. 4. Novel on-line mid infrared detection strategies in capillary electrophoretic systems

    Author : Malin Kölhed; Bo Karlberg; Sven P. Jacobsson; Andre' J. Sommer; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; on-line hyphenation; mid infrared detection; capillary electrophoresis; FTIR; quantum cascade laser; aqueous samples; Analytical chemistry; Analytisk kemi;

    Abstract : Infrared absorption spectra can provide analytically useful information on a large variety of compounds, ranging from small ions to large biological molecules. In fact, all analytes that possess a dipole moment that changes during vibration are infrared-active. The infrared (IR) spectrum can be subdivided into far-, mid- and near- regions. READ MORE

  7. 5. Detection in liquid chromatography by means of UV-absorbing or fluorescent system components

    Author : Lars Hackzell; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PHARMACY; FARMACI;

    Abstract : .... READ MORE