Search for dissertations about: "UVR-B"

Showing result 1 - 5 of 6 swedish dissertations containing the word UVR-B.

  2. 1. Cataract induced by UVR-B 300nm : characterization and genetic modulation of the lens sensitivity to oxidative stress

    Author : Linda Maren Meyer; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Lens; cataract; ultraviolet radiation; oxidative stress; Grx1; interleukins;

    Abstract : Cataract is defined as an opacification of the lens resulting in visual impairment. Worldwide, it is the number one cause of blindness and there are currently no strategies to prevent the onset of the disease. Cataract surgery is the most commonly performed elective intervention in industrialized countries. READ MORE

  4. 2. Caspase-3 in lens epithelium

    Author : Nooshin Talebizadeh; Per Söderberg; Finn Hallböök; Konstantin Galichanin; Michael Wormstone; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ultraviolet radiation; caspase-3; lens; cataract; apoptosis; Immunohistochemistry; spatial distribution; time evolution; modelling; automatic analysis; cell counting; image analysis.; Ophtalmology; Oftalmiatrik;

    Abstract : Purpose: To model the time evolution of active caspase-3 protein expression in a healthy lens, and in a lens exposed to UVR-300 nm (UVR-B). To develop an automated method to classify the fluorescent signal of biomarkers in the lens epithelial cells.Methods: Six-week old Sprague-Dawley rats were used. READ MORE

  5. 3. Cataract from ultraviolet radiation in the mouse

    Author : Linda Maren Meyer; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Lens; cataract; ultraviolet radiation; oxidative stress; mouse; light scattering;

    Abstract : Cataract is defined as an opacification of the crystalline lens that results in visual impairment, Cataract is the number one cause of blindness in the world and there are currently no strategies to prevent it. Extraction of cataractogenous lenses is the most commonly performed surgical intervention in industrialized countries. READ MORE

  6. 4. Ultraviolet radiation cataract

    Author : Konstantin Galichanin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : lens;

    Abstract : Cataract is the leading cause of blindness in the world. Epidemiological and experimental evidence supports a link between mid-range ultraviolet radiation (UVR-B) exposure and the development of cataract. READ MORE

  7. 5. Safety limit estimation for cataract induced by ultraviolet radiation

    Author : Xiuqin Dong; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Ultraviolet radiation UVR ; Sprague-Dawley rat; cataract; light scattering; doseresponse function; maximum acceptable dose MAD ; maximum tolerable dose MTD ; in vivo; in vitro; age.;

    Abstract : Background: Ultraviolet radiation (UVR) is considered one of the major risk factors for agerelated cataract. UVR-induced cataract follows a continuous dose-response function. READ MORE