Search for dissertations about: "Ulf Gyllensten"

Showing result 11 - 15 of 23 swedish dissertations containing the words Ulf Gyllensten.

  2. 11. Contribution of Immunogenetic Factors in Susceptibility to Cervical Cancer

    Author : Emma Ivansson; Ulf Gyllensten; Patrik Magnusson; Allan Hildesheim; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medical genetics; Medicinsk genetik;

    Abstract : Cervical cancer is the second most common cancer in women worldwide. Persistent infection by an oncogenic type of human papillomavirus (HPV) is a necessary but not sufficient cause and there is also a genetic component. READ MORE

  4. 12. Genome Variation in Human Populations : Exploring the Effects of Demographic History and the Potential for Mapping of Complex Traits

    Author : Åsa Johansson; Ulf Gyllensten; Marta Alarcon; Andrew Clark; Uppsala universitet; []
    Keywords : Genetics; genetics; evolution; microsatellie; SNP; selection; linkage disequilibrium; haplotype; Genetik;

    Abstract : A major challenge in human genetics is to understand the genetic variation underlying common diseases. In this thesis, I focus on forces creating differences between individuals and genomic regions, methods for characterizing genomic variation, and the association between genomic and phenotypic variation. READ MORE

  5. 13. Analysis of genetic susceptibility to cervical cancer using candidate gene and GWAS approaches

    Author : Ivana Juko-Pecirep; Ulf Gyllensten; Holger Luthman; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cervical cancer; association study; human papillomavirus; genetics; complex disease; TMC6; TMC8; MHC region; Medical Genetics; Medicinsk genetik;

    Abstract : Cervical cancer is the forth most commonly diagnosed cancer among women worldwide. It is caused by persistent infection with an oncogenic type of Human Papillomavirus (HPV). The HPV is a necessary but not sufficient cause of cervical cancer. READ MORE

  6. 14. On Transcriptome Sequencing

    Author : Daniel Klevebring; Joakim Lundeberg; Ulf Gyllensten; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transcriptome; RNA-seq; DNA sequencing; gene expression profiling; non-coding RNA; small RNA; Functional genomics; Funktionsgenomik; Bioinformatics; Bioinformatik; Genetics; Genetik; Molecular biology; Molekylärbiologi; Cell biology; Cellbiologi;

    Abstract : This thesis is about the use of massive DNA sequencing to investigate the transcriptome. During recent decades, several studies have made it clear that the transcriptome comprises a more complex set of biochemical machinery than was previously believed. READ MORE

  7. 15. Functional Role of Genetic Polymorphisms Associated with Systemic Lupus Erythematosus

    Author : Sara E Löfgren; Ulf Gyllensten; Jan Hillert; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; autoimmunity; systemic lupus erythematosus; genetic association; single nucleotide polymorphism; IRF5; CD226; miR-146a; Medical Science; Medicinsk vetenskap; Medical Genetics; Medicinsk genetik;

    Abstract : Systemic lupus erythematosus (SLE) is a chronic and complex autoimmune disorder characterized by a failure in the mechanism of self-tolerance and production of autoantibodies, potentially affecting any organ in the body. The genetic factors behind the disease have been extensively studied in the past years and to date a list of more than 30 loci have been associated with SLE. READ MORE