Search for dissertations about: "Understanding antibiotic resistance"

Showing result 1 - 5 of 73 swedish dissertations containing the words Understanding antibiotic resistance.

  2. 1. Antibiotic Resistance : Selection in the Presence of Metals and Antimicrobials

    Author : Lisa M. Albrecht; Dan I Andersson; Alex O'Neill; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Antibiotic resistance; Metals; Antimicrobials; Bacterial evolution; Bacterial genetics; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Abstract : The external environment is complex: Antibiotics, metals and antimicrobials do not exist in isolation but in mixtures. Human activities such as animal husbandry, fertilization of agricultural fields and human medicine release high amounts these compounds into the environment. READ MORE

  4. 2. Extended-Spectrum ß-Lactamase-Producing Enterobacteriaceae : Antibiotic consumption, Detection and Resistance Epidemiology

    Author : Åse Östholm Balkhed; Lennart Nilsson; Håkan Hanberger; Hans-Jurg Monstein; Anita Hällgren; Mats Kalin; Linköpings universitet; []
    Keywords : Extended-Spectrum ß-Lactamase-Producing Enterobacteriaceae; Antibiotic consumption; Detection Methods; Multiplex PCR; Resistance Epidemiology; Multi-resistance; E. coli; ESBL; fecal carriage; faecal carriage; travel;

    Abstract : ESBL-producing Enterobacteriaceae are emerging worldwide and they are frequently multi-drug resistant, thus limiting treatment options for infections caused by these pathogens.The overall aim of the thesis was to investigate ESBL-producing Enterobacteriaceae in a Swedish county. READ MORE

  5. 3. Mechanisms of Antibiotic Resistance Evolution

    Author : Michael Knopp; Dan Andersson; Anca Segall; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Antibiotic resistance evolution; Escherichia coli; Salmonella; porins; fitness; epistasis; strain-specificity; sub-MIC; de novo gene evolution;

    Abstract : The continuing emergence and spread of antibiotic resistant bacteria are a threat to various applications in modern medicine and impose a strong economic burden on health systems. The development of new antibiotics is slow and cannot counterbalance the dissemination of resistant bacteria. READ MORE

  6. 4. Antibiotic resistance in the environment: a contribution from metagenomic studies

    Author : Johan Bengtsson-Palme; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; antibiotic resistance; metagenomics; bioinformatics; next generation sequencing; resistance selection;

    Abstract : Antibiotic resistance accounts for hundreds of thousands of deaths annually, and its projected increase has made the WHO recognize it as a major global health threat. In the last decade, evidence has mounted suggesting that the environment plays an important role in the progression of resistance. READ MORE

  7. 5. Evolution of Antibiotic Resistance

    Author : Franziska Pietsch; Diarmaid Hughes; Josep Casadesús; Uppsala universitet; []
    Keywords : ciprofloxacin; rifampicin; bacterial fitness; compensation; mutation rate; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Abstract : The emergence of antimicrobial resistance is a major global threat to modern medicine. The rapid dissemination of resistant pathogens and the associated loss of efficacy of many important drugs needs to be met with the development of new antibiotics and alternative treatment options. READ MORE