Search for dissertations about: "Urothelial Carcinoma"

Showing result 1 - 5 of 13 swedish dissertations containing the words Urothelial Carcinoma.

  2. 1. MOLECULAR PROFILING OF UROTHELIAL CARCINOMA

    Author : David Lindgren; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cytogenetik; Urology; nephrology; Urologi; nefrologi; Clinical genetics; Klinisk genetik; cytogenetics; Genetics; cancer; onkologi; Cytologi; cancerology; oncology; Cytology; TP53; FGFR3; gene expression profiling; microarray; bladder cancer; urothelial carcinoma; Genetik;

    Abstract : The general aim of this thesis was to molecularly characterize urothelial carcinoma (UC) at the transcriptional level using gene expression microarrays to improve the classification and pathogenetic understanding of this disease. In the first two studies (Articles I and II), gene expression profiling was used to study dysregulated transcriptional networks in a large cohort of UCs. READ MORE

  4. 2. Epigenetic and Phenotypic Profiling of Urothelial Carcinoma

    Author : Mattias Aine; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epigenetics; DNA methylation; gene expression; urothelial carcinoma; bladder cancer;

    Abstract : Precise spatial and temporal regulation of gene expression programs is a prerequisite for multicellular life. Since the discovery of DNA as the carrier of genetic information, a key question in biology has been how these hard coded instructions are read and regulated to maintain cellular and organismal homeostasis. READ MORE

  5. 3. Upper-tract urothelial carcinoma : diagnostics and prognostic factors

    Author : Camilla Malm; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Upper-tract urothelial carcinoma (UTUC) is rare, constituting 5-10% of all urothelial cancers. Urothelial carcinoma of the bladder is a common disease and is more studied than UTUC. READ MORE

  6. 4. Stage T1 Urinary Bladder Carcinoma : Investigation of A Population-Based Cohort

    Author : Hans Olsson; Staffan Jahnson; Per Hultman; Peter Söderkvist; Sten Nilsson; Linköpings universitet; []
    Keywords : ;

    Abstract : Approximately 2 300 new cases of urinary bladder carcinoma (UBC) are diagnosed every year in Sweden. This type of cancer is characterized as a long-standing disease with a high risk of recurrence and progression from an indolent to a more aggressive course. READ MORE

  7. 5. Molecular Characterization of Bladder Cancer Subtypes

    Author : Pontus Eriksson; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bladder Cancer; Urothelial Carcinoma; Molecular Subtypes; Genomic Characterization; Gene Expression;

    Abstract : Bladder cancer is one of the most common malignancies world-wide, and in Sweden approximately 3000 cases are diagnosed annually. Even though bladder cancer is so common there is low public awareness of the disease, and it has historically been less studied compared to other common types of cancer. READ MORE