Search for dissertations about: "V gene"

Showing result 11 - 15 of 597 swedish dissertations containing the words V gene.

  2. 11. Clinical aspects of molecular profiles in metastatic malignant melanoma

    Author : Henrik Ekedahl; Lund Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Melanom; Prognos; BRAF; TERT; Genuttryck; Next generation sequencing; Melanoma; Prognosis; BRAF; TERT; Gene Expression; Next generation sequencing;

    Abstract : Malignant melanoma is a heterogeneous, malignant neoplastic disease, most often originating in the skin. Melanoma is characterized by a high mutational load and has a vastly variable prognosis, depending on disease stage. READ MORE

  4. 12. Predictors of Lymph Node Metastasis in Primary Breast Cancer - Risk Models for Tailored Axillary Management

    Author : Looket Dihge; Lund Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast Cancer; Axillary lymph node dissection; Sentinel lymph node biopsy; Ultrasonography; Nomogram; Artificial neural network; Gene Expression; Prediction model;

    Abstract : Most patients with breast cancer present with low-risk tumors, node-negative disease, and excellent prognosis. For these patients, routine axillary nodal staging by sentinel lymph node biopsy (SLNB) has no therapeutic benefit. For patients with limited sentinel lymph node metastasis, completion axillary nodal dissection is controversial. READ MORE

  5. 13. The Plasminogen Activation System in Human Endometrium and Endometrial Cancer; Function, Tissue Localization and Prognostic Importance

    Author : Johanna Nordengren; Lund Obstetrik och gynekologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics; progesterone; estradiol; cultured cells; gene expression; prognosis; hyperplasia; neoplasm; endometrium; human; Plasminogen activators; gynaecology; andrology; reproduction; sexuality; Obstetrik; gynekologi; andrologi; reproduktion; sexualitet;

    Abstract : The release of urokinase plasminogen activator (uPA) from endometrial stromal cells decreased after progesterone stimulation, due to upregulation of PA inhibitor 1 (PAI-1) and uPA receptor (uPAR). Subsequently, the uPA:PAI-1 complex was internalized and degraded via uPAR. READ MORE

  6. 14. Myocardial gene therapy and gene expression in angina pectoris

    Author : Andreas Rück; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Angina pectoris; gene therapy; vascular endothelial growth factor; plasmid; prognosis; collaterals; angiogenesis; gene expression; microarray; natriuretic peptides.;

    Abstract : Background: Angiogenesis does not fully counteract myocardial ischemia in stable angina pectoris. Refractory angina pectoris, with remaining symptoms despite medication and no possibility for bypass surgery or angioplasty, is rather common. Angiogenic gene therapy is a novel treatment strategy for these patients. READ MORE

  7. 15. Spatial Models of Gene Patterns in Plants

    Author : André Larsson; Institutionen för astronomi och teoretisk fysik - Genomgår omorganisation; []
    Keywords : computational morphodynamics; gene regulation; spatial models; plants; development; auxin; meristem; Fysicumarkivet A:2017:Larsson;

    Abstract : The growth and development of plants exhibits a striking symmetry, visible in the regular arrangement of leaves and flowers. Plant development is carefully controlled at the molecular level by gene regulatory networks, and the symmetry of plants can be observed also in the molecular patterns of gene expression. READ MORE