Search for dissertations about: "V gene"

Showing result 16 - 20 of 597 swedish dissertations containing the words V gene.

2. 16. Gene Regulatory Networks: Dynamics and Stability

   Author : Carl Troein; Beräkningsbiologi och biologisk fysik - Genomgår omorganisation; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; systems; control; Datalogi; numerisk analys; system; kontroll; Computer science; numerical analysis; Fysik; biomathematics biometrics; Bioinformatik; medicinsk informatik; biomatematik; Physics; medical informatics; transcriptional regulation; gene regulatory networks; Bioinformatics; signaling pathway profiling; stem cell regulation; metabolic pathway; fitness; nested canalyzing rules; Kauffman networks; random Boolean networks; Fysicumarkivet:2007:Troein;

   Abstract : Life as we know it is based on cells that use proteins and RNA to carry out metabolism, self-replication, and other essential tasks. The genes that code for these molecules are encoded in DNA, and through the processes of transcription and translation the cell expresses its genes. READ MORE

4. 17. Robust inference of gene regulatory networks : System properties, variable selection, subnetworks, and design of experiments

   Author : Torbjörn E. M. Nordling; Elling W Jacobsen; Rolf Findeisen; KTH; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; network inference; reverse engineering; variable selection; model selection; feature selection; subset selection; system identification; system theory; network theory; subnetworks; design of experiments; perturbation experiments; gene regulatory networks; biological networks;

   Abstract : In this thesis, inference of biological networks from in vivo data generated by perturbation experiments is considered, i.e. deduction of causal interactions that exist among the observed variables. Knowledge of such regulatory influences is essential in biology. READ MORE

5. 18. Gene therapy in epilepsy: neuropeptides and neurotrophic factors

   Author : Irene Kanter Schlifke; Lund Wallenberg Neurocentrum; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurologi; neurophysiology; neuropsychology; Neurology; piriform cortex; hippocampus; neuropsykologi; encapsulated cells; viral vectors; GDNF; galanin; epilepsy; gene therapy; neurofysiologi;

   Abstract : Temporal lobe epilepsy (TLE) is the most common form of epilepsy among adult patients, and the most problematic one as seizures cannot be controlled by currently available drugs in 30 % of patients. Gene therapy based on overexpression of endogenous anti-epileptic agents such as the neuropeptide galanin and the glial cell line-derived neurotrophic factor (GDNF) represents a promising new approach for treatment of TLE. READ MORE

6. 19. Vector development for suicide gene therapy

   Author : Alar Aints; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Suicide gene therapy; VP22; selection markers; Ouabain resistance gene; GvHD; retroviral gene transfer;

   Abstract : Gene therapy is used to treat conditions that arise from errors in the genetic makeup of cells either congenital diseases resulting from a deletion or mutation in a gene or malignant diseases where genetic regulation mechanisms have been deranged. Suicide gene therapy is one of several gene therapeutic approaches to treat cancer. READ MORE

7. 20. Fibrinogen and susceptibility to myocardial infarction : role of gene-gene and gene-environment interactions

   Author : Maria Nastase Mannila; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Atherothrombosis; epistasis; fibrinogen; fibrinogen gamma; fibrin clot structure; haplotypes; myocardial infarction; pleiotropy; SNPs;

   Abstract : Fibrinogen, the precursor of fibrin, is a glycoprotein synthesized in the liver and maintained in plasma at concentrations normally ranging between 2-4 g/L. The fibrinogen molecule consists of two sets of three non-identical polypeptide chains, which are encoded by the fibrinogen gamma (FGG), fibrinogen alpha (FGA) and fibrinogen beta (FGB) genes clustered on chromosome 4. READ MORE