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Showing result 1 - 5 of 38 swedish dissertations matching the above criteria.

2. 1. Soluble intercellular and vascular cell adhesion molecules-1 in lymphoid neoplasms : A clinical and prognostic study of Hodgkin's disease, non-Hodgkin's lymphomas and chronic B-lymphocytic leukaemia

   Author : Ilse Christiansen; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Hodgkin s disease; non-Hodgkin s lymphomas; chronic lymphocytic leukaemia; sICAM-1; sVCAM-1; prognostic markers; VCAM-1; ICAM-1; Hodgkin cell lines; Onkologi; Oncology; Onkologi; Clinical Immunology; klinisk immunologi;

   Abstract : The interaction of soluble adhesion molecules with adhesion ligands expressed by immunological cells interfere with the cell-cell adhesion essential for the signal transductions that initiate immunological responses. Preliminary data suggest that soluble adhesion molecules also promote angiogenesis. READ MORE

4. 2. Inflammatory mediators in diabetic retinopathy

   Author : Carin Gustavsson; Malmö Institutionen för kliniska vetenskaper; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; inflammation; dyslipidemia; diabetic retinopathy; oxidative stress; TNF-alpha; VCAM-1;

   Abstract : Diabetic retinopathy (DR) is the most feared complication of diabetes with an overall prevalence of 21.9-36.8% and may, if untreated, lead to severe visual disability or blindness. READ MORE

5. 3. Vascular and metabolic effects of selective PDE-5 inhibition - clinical and experimental studies

   Author : Lovisa Sjögren; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 diabetes; MAPK; phosphodiesterase-5 inhibition; JNK; endothelial cells; E-selectine; VCAM-1; HUVEC; TNFa; ICAM-1; inflammation;

   Abstract : ABSTRACT Vascular and metabolic effects of selective PDE-5 inhibition Clinical and experimental studies Lovisa Sjögren Department of Molecular and Clinical Medicine, Institute of Medicine at Sahlgrenska Academy, University of Gothenburg Key words: Type 2 diabetes, phosphodiesterase-5 inhibition, inflammation, endothelial cells, HUVEC. TNFα, ICAM-1, VCAM-1, E-Selectin, JNK, MAPK Background: Type 2 diabetes (T2D) patients show impaired glucose metabolism, endothelial dysfunction, chronic low-grade inflammation as well as an increased risk of cardiovascular disease. READ MORE

6. 4. NFAT signaling in chronic and acute inflammation - A novel target for the treatment of diabetic vascular complications and acute pancreatitis?

   Author : Anna Zetterqvist; Diabetiska komplikationer; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NFAT; vascular; diabetes; inflammation; atherosclerosis; diabetic retinopathy; acute pancreatitis; osteopontin; VCAM-1; A-285222;

   Abstract : Diabetic patients suffer from macro- and microvascular complications causing increased morbidity and mortality. How hyperglycemia provokes vascular damage remains unclear, but glucose is believed to fuel a harmful low-grade chronic inflammation of the vessel wall. READ MORE

7. 5. Regulation of leukocyte integrin adhesiveness

   Author : Håkan Hedman; Erik Lundgren; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lymphocytes; Cell Adhesion; Integrins; LFA-1; VLA-4; ICAM-1; VCAM-1; Microvesicles; Protein Kinases; Protein Phosphatases;

   Abstract : .... READ MORE