Search for dissertations about: "VEGF-A"

Showing result 1 - 5 of 58 swedish dissertations containing the word VEGF-A.

  1. 1. The importance of astroglial cells in ischemia, regeneration and angiogenesis

    Author : Andrea Lundkvist; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : astrocytes; Müller cells; retina; intermediate filaments; GFAP; vimentin; angiogenesis; VEGF-A; guidance; matrix-metalloprotease;

    Abstract : Astrocytes in the CNS communicate with both neurons and blood vessels. In many CNS pathologies, astrocytes respond by becoming reactive. Whether their performance at this stage is beneficial or detrimental for CNS function is unclear. READ MORE

  2. 2. Molecular Mechanisms in Endothelial Cell Differentiation

    Author : Emma Rennel; Pär Gerwins; Lena Claesson-Welsh; Ian Zachary; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; angiogenesis; FGF-2; VEGF-A; signal transduction; in vitro angiogenesis assay; immortalized brain endothelial cells; H-Ras; tetracycline-regulated gene expression; microarray; telomerase immortalized human microvascular endothelial cells; differentiation; Patologi; Pathology; Patologi;

    Abstract : Angiogenesis is the formation of new blood vessels from the pre-existing blood vessels. Blood vessels are composed of endothelial cells and supporting musculature. Angiogenesis is regulated by numerous soluble ligands and by cell-matrix interactions. READ MORE

  3. 3. Oxidative Stress, Angiogenesis and Inflammation in Normal Pregnancy and Postpartum

    Author : Maria Palm; Ove Axelsson; Samar Basu; Charlotta Grunewald; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Angiogenesis; inflammation; IL-6; F2-isoprostanes; oxidative stress; Pentraxin 3; PGF2α; PlGF; pregnancy; sFlt1; TNF-α; VEGF-A; Obstetrik och gynekologi; Obstetrics and Gynaecology; Medicinsk vetenskap; Medical Science;

    Abstract : The aims were to investigate oxidative stress (I), angiogenesis (II) and inflammation (III-IV) in healthy women during pregnancy and postpartum. Oxidative stress was estimated by measurement of 8-iso-PGF2α and the antioxidants α- and γ-tocopherol. READ MORE

  4. 4. Leukocytes in Angiogenesis : Learning from Transplanted Pancreatic Islets

    Author : Gustaf Christoffersson; Mia Phillipson; Kristian Pietras; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; angiogenesis; pancreatic islet transplantation; islets of Langerhans; diabetes mellitus; leukocytes; neutrophils; macrophages; pericytes; MMP-9; VEGF-A; Medical Science; Medicinsk vetenskap;

    Abstract : Angiogenesis, the growth of new blood vessels, is a complex process involving several cell types and molecular signals. Excessive vascular growth is a problem in tumors, and insufficient vascularization hampers the function of transplanted insulin-producing pancreatic islets. READ MORE

  5. 5. Exploring immune cell functions and ways to make use of them

    Author : Evelina Vågesjö; Mia Phillipson; Michael Hickey; Uppsala universitet; []
    Keywords : leukocytes; neutrophils; macrophages; regulatory T cells; chemokines; VEGF-A; hypoxia; ischemia; muscle; Islets of Langerhans; diabetes; transplantation; wound healing;

    Abstract : In addition to host defense, alternative functions of immune cells are emerging. Immune cells are crucial during healing of injured tissue, in formation of new blood vessels, angiogenesis, and also in maintaining the balance in inflammation having immune regulating functions. READ MORE