Search for dissertations about: "VEGF-A"

Showing result 16 - 20 of 60 swedish dissertations containing the word VEGF-A.

  2. 16. Identification and Characterization of Proteins and MicroRNAs that Modulate Receptor Signaling, Vesicular Trafficking and Cell Migration in Vascular Cells

    Author : Johan Heldin; Johan Kreuger; Jonas Fuxe; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Angiogenesis; cell migration; signaling; VEGF; FGD5; ExoC3L2; microRNA; RhoD; Molekylär cellbiologi; Molecular Cellbiology;

    Abstract : Blood vessels deliver nutrients and oxygen to tissues. Importantly, the functions and growth of blood vessels are commonly altered in disease. The inside of all blood vessels are lined with endothelium, a thin specialized layer of endothelial cells that separate the blood from other tissues. READ MORE

  4. 17. Fibroblast Growth Factor Receptor-1 Function in Vasculo- and Angiogenesis

    Author : Peetra Magnusson; Lena Claesson-Welsh; Anne Eichmann; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; FGF; FGFR-1; VEGFR-2; PDGFR-β; endothelial cells; embryonic stem cell; angiogenesis; hematopoiesis; Patologi; Pathology; Patologi;

    Abstract : During development of the mammalian embryo, spatial and temporal expression of fibroblast growth factors (FGFs) and their cognate receptors are vital in the regulation of a number of patterning processes. Inappropriate or decreased expression leads to severe malformations and even embryonic death. READ MORE

  5. 18. The Roles of Growth Factor Interactions and Mechanical Tension in Angiogenesis

    Author : Ludvig Petersson; Pär Gerwins; Filip Farnebo; Uppsala universitet; []
    Keywords : angiogenesis; myofibroblast; wound healing; VEGF; FGF; PDGF; endocan; endothelial cell; vascularization; MEDICINE; MEDICIN; Medicin; Medicine;

    Abstract : Angiogenesis, the formation of new blood vessels from preexisting ones through creation of new vessel branch points by sprouting or vessel splitting, is an important part of tissue growth in both physiological processes like wound healing and pathological conditions such as cancer. Growth factors like VEGF-A, FGF-2 and PDGF-BB are involved in both types of angiogenesis. READ MORE

  6. 19. The Human Endometrium : Studies on Angiogenesis and Endometriosis

    Author : Christian Moberg; Matts Olovsson; Anneli Stavreus-Evers; Lalit Kumar Parameswaran Grace; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; endometrium; angiogenesis; endothelial cell; endometriosis; receptivity; implantation; oestrogen receptor; progesterone receptor; crystallin; interleukin; vasoactive intestinal peptide; peritoneal fluid; Obstetrik och gynekologi; Obstetrics and Gynaecology;

    Abstract : Angiogenesis is thought to play a pivotal role in the cycling endometrium. Coordinated by oestrogen and progesterone, endometrial blood vessel development is primarily mediated by vascular endothelial growth factor-A (VEGF-A), which promotes endothelial cell (EC) proliferation and protects ECs from induced apoptosis. READ MORE

  7. 20. Idiopathic menorrhagia : studies of angiogenesis and surgical therapy

    Author : Miriam Mints; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Menorrhagia; TCRE; endometrium; angiogenesis; VEGF; VEGFR1; -2; -3; gaps.;

    Abstract : Background: Excessive menstrual bleeding, menorrhagia (i.e. > 80 nil loss of blood) is a com-mon gynecological problem in women of reproductive age, accounting for over 20% of visits to gynecology outpatient clinics. The disorder may not only cause iron deficiency anemia but also considerable social discomfort and reduction in the quality of life. READ MORE