Search for dissertations about: "VEGF"

Showing result 16 - 20 of 244 swedish dissertations containing the word VEGF.

  2. 16. Human Endometrial Angiogenesis : An Immunohistochemical Study of the Endometrial Expression of Angiogenic Growth Factors and Their Corresponding Receptors

    Author : Björn Möller; Matts Olovsson; Bo Lindblom; Kristina Gemzell-Danielsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Human endometrium; angiogenesis; menstrual cycle; endothelial cells; immunohistochemistry; western blot; VEGF; VEGFR; FGF-2; FGFR; EGF; EGFR; levonorgestrel-releasing intrauterine system; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

    Abstract : The human endometrium undergoes dramatic changes in morphology and function during the menstrual cycle. Recurrent angiogenesis (the formation of new blood vessels) is of utmost importance for oxygen supply and nourishment of the rapidly growing endometrial tissue. READ MORE

  4. 17. Development of 18F- and 68Ga-Labelled Tracers : Design Perspectives and the Search for Faster Synthesis

    Author : Elisabeth Blom; Bengt Långström; Oleksiy Itsenko; Irina Velikyan; Farhad Karimi; Frank Rösch; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; PET; nucleophilic 18F-fluorination; perfluoro; F-SPE; molecular design; 68Ga; chelators; DOTA; NOTA; microwave; halogen exchange; harmine; biotin; RGD; VEGF; CRP; Chemistry; Kemi; Organisk kemi; Organic Chemistry;

    Abstract : This thesis deals with the design of 18F- and 68Ga-labelled positron emission tomography (PET) tracers and the development of technologies that enable faster and simpler preparation with high specific radioactivity. Techniques like microwave heating and reducing the concentrations of the precursor were investigated with this perspective. READ MORE

  5. 18. Molecular Mechanisms of Action of Histidine-rich Glycoprotein in Angiogenesis Inhibition

    Author : Chunsik Lee; Lena Claesson-Welsh; Jan Palmblad; Uppsala universitet; []
    Keywords : Cell and molecular biology; anti-angiogenesis; angiogenesis inhibitor; endothelial cell; histidine-rich glycoprotein; focal adhesion; tumor-associated macrophages; VEGF; MMP; Cell- och molekylärbiologi;

    Abstract : Angiogenesis, de novo synthesis of blood vessels from the pre-existing vasculature, is required both during embryonic development and in pathophysiological conditions. In particular, tumor growth needs new capillary vessels in order to both deliver oxygen and nutrients and to remove toxin and metabolites. READ MORE

  6. 19. Experimental therapies of malignant glioma : with emphasis on angiogenesis inhibition

    Author : Maria Sandström; Roger Henriksson; Mikael Johansson; Anja Smits; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glioma; angiogenesis; VEGF; tyrosinekinaseinhibitor; ZD6474; plasminogenactivator; tPA; uPA; proteomics; Oncology; Onkologi;

    Abstract : Malignant glioma consists of a group of diseases where the localisation and the nature of the disease makes treatment an extreme challenge. Two important biological features of malignant glioma cells are their infiltrative growth and their ability to induce angiogenesis. READ MORE

  7. 20. Risk and prognostic factors for malignant glioma

    Author : Sara Sjöström; Beatrice S Melin; Ulrika Andersson; Monika Hegi; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioma; Glioblastoma; Risk; Outcome; EGR; EGFR; VEGF; VEGFR; DNA repair; virus; Oncology; Onkologi; onkologi; Oncology;

    Abstract : Background: Glioblastoma is the most common and aggressive type of glioma and associated with poor prognosis. Apart from ionizing radiation and some rare genetic disorders, few aetiological factors have been identified for primary brain tumours. READ MORE