Search for dissertations about: "VEGFR-2"

Showing result 11 - 15 of 25 swedish dissertations containing the word VEGFR-2.

  1. 11. Macrophage expression of VEGF and VEGFR-1. Potential involvement in atherogenesis

    Author : Linda Salomonsson; Göteborgs universitet; []
    Keywords : atherosclerosis; macrophages; oxLDL; statins; VEGF; VEGFR-1;

    Abstract : The vascular endothelial growth factor (VEGF) family is a group of proteins which contributes to both neovascularisation and inflammation. Elevated levels of VEGF have been found in subjects with atherosclerosis and correlate to several cardiovascular risk factors, e.g. hypertension and hyperlipidemia. READ MORE

  2. 12. Androgen controlled regulatory systems in prostate cancer : potential new therapeutic targets and prognostic markers

    Author : Peter Hammarsten; Anders Bergh; Stina Häggström Rudolfsson; Pernilla Wikström; Sten Nilsson; Umeå universitet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; prostate cancer; angiogenesis; human biopsy; androgen ablation; castration; prognostic marker; prognostic factor; growth control; VEGF; vascular endothelial growth factor; EGFR; epidermal growth factor receptor; pEGFR; phosphorylated EGFR; phosphorylated epidermal growth factor receptor; Pathology; Patologi;

    Abstract : BACKGROUND: Prostate cancer is by far the most common cancer among Swedish men. Some patients have an aggressive lethal disease, but the majority of affected men have long expected survival. Unfortunately, the diagnostic tools available are insufficient in predicting disease aggressiveness. Novel prognostic markers are therefore urgently needed. READ MORE

  3. 13. VEGF-mediated vascular functions in health and disease

    Author : Ziquan Cao; Eric Wahlberg; Yihai Cao; Toste Länne; Kayoko Hosaka; Jack L. Arbiser; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Angiogenesis is essential for physiological processes including embryonic development, tissue regeneration, and reproduction. Under various pathological conditions the same angiogenic process contribute to the onset, development, and progression of many human diseases including cancer, diabetic complications, ocular disease, chronic inflammation and cardiovascular disease. READ MORE

  4. 14. The role of VEGF family in angiogenesis, tumor growth and metastasis

    Author : Xiaojuan Yang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Tumor growth is dependent on angiogenesis, and cells in tumor tissues produce various angiogenic factors to induce neovascularization. Among tumor-derived angiogenic factors, members of the vascular endothelial growth factor (VEGF) family are most frequently and highly expressed in various solid tumors. READ MORE

  5. 15. Application of proximity Ligation for Detection of Proteins, Biomolecular Interactions, and Single Copies of Pathogens

    Author : Sigrun Margret Gustafsdottir; Ulf Landegren; Per-Åke Nygren; Uppsala universitet; []
    Keywords : Molecular medicine; Proximity ligation; Cytokines; Microbial pathogens; Protein-DNA interactions; Drug screening; Molekylärmedicin;

    Abstract : Proximity ligation is a recently established technique that can provide answers to questions about the concentration, localization, interactions, modifications and functions of proteins. The method enables sensitive protein measurements with a detection limit in the low femtomolar range in complex biological samples. READ MORE