Search for dissertations about: "VLDL"

Showing result 1 - 5 of 50 swedish dissertations containing the word VLDL.

  2. 1. Effects of ARF1 and phospholipase D on the assembly and secretion of apoB-100 containing lipoproteins

    Author : Lennart Asp; Göteborgs universitet; []
    Keywords : ApoB; ARF1; Phospholipase D; Lipoproteins; VLDL; ; Lipid droplets.;

    Abstract : Hydrophobic insoluble lipids such as triglycerides and cholesterol ester are transported in spherical, water-soluble molecular complexes called lipoproteins. Lipoproteins are secreted mainly from the liver and intestine into the plasma for distribution to peripheral tissues. READ MORE

  4. 2. The assembly and secretion of ApoB containing lipoproteins

    Author : Pia Stillemark; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Apolipoprotein B; lipoprotein; VLDL; microsomal triglyceride transfer protein; chaperone;

    Abstract : Increased levels of cholesterol and triglycerides in the blood are important risk factors for the development of premature atherosclerosis and its complications such as coronary-heart diseases, stroke and peripheral vascular diseases. These diseases are the major causes of death in Europe, USA and part of Asia. READ MORE

  5. 3. Growth hormone and PPARa in the regulation of lipoprotein metabolism

    Author : Daniel Lindén; Göteborgs universitet; []
    Keywords : growth hormone; insulin; fatty acids; PPARa; apolipoprotein B; VLDL; mRNA editing;

    Abstract : In humans, apolipoprotein B (apoB)-100 is produced in the liver and apoB-48 is formed in the intestine. In the rat, however, the two forms of apoB are produced in the liver, leading to the formation of VLDL consisting of either apoB-48 or apoB-100. READ MORE

  6. 4. Studies on the atherogenicity of apoB-containing lipoproteins in type 2 diabetes

    Author : Camilla Pettersson; Göteborgs universitet; []
    Keywords : Type 2 diabetes; metabolic syndrome; atherosclerosis; VLDL; LDL; secretory phospholipase A2 group V; inflammation; complement; apolipoprotein; lysozyme;

    Abstract : Type 2 diabetes (T2D) and the metabolic syndrome (MetS), two conditions that are rapidly increasing in prevalence, as well as the dyslipoproteinemia and subclinical inflammation characteristic for these conditions, are associated with an increased risk for developing and dying of cardiovascular disease (CVD). The aim of this thesis was to investigate possible atherogenic properties of very low-density lipoprotein (VLDL) and low-density lipoprotein (LDL) in T2D and MetS. READ MORE

  7. 5. Early perturbations in lipid metabolism in insulin resistance

    Author : Else Hellebö Johanson; Göteborgs universitet; []
    Keywords : insulin resistance; nateglinide; peak VO2; postprandial; relatives; triglyceride-rich lipoproteins; visceral fat; VLDL;

    Abstract : Subjects with the Metabolic Syndrome with or without type 2 diabetes are at excess risk for developing cardiovascular disease. The mechanisms are still not completely understood. Resistance to insulin-stimulated glucose uptake is associated with several metabolic and hemostatic risk factors for cardiovascular disease. READ MORE