Search for dissertations about: "VPC"

Found 5 swedish dissertations containing the word VPC.

  2. 1. VPC Management in ATM Networks

    Author : Sven-Olof Larsson; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; ATM; Virtual Paths; Capacity Management; Resource Allocation;

    Abstract : .... READ MORE

  4. 2. Application of Mixed-Effect Modeling to Improve Mechanistic Understanding and Predictability of Oral Absorption

    Author : Martin Bergstrand; Mats O Karlsson; Hans Ericsson; Bart Ploeger; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Absorption; magnetic marker monitoring; drug release; IVIVC; pharmacometrics; NONMEM; model diagnostics; pcVPC; pvcVPC; visual predictive check; VPC; BQL; paracetamol; sulfapyridine.; Other pharmacy; Övrig farmaci; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi;

    Abstract : Several sophisticated techniques to study in vivo GI transit and regional absorption of pharmaceuticals are available and increasingly used. Examples of such methods are Magnetic Marker Monitoring (MMM) and local drug administration with remotely operated capsules. READ MORE

  5. 3. Methods for handling model misspecification in pharmacometric model-based approaches for the analysis of longitudinal clinical trial data

    Author : Estelle Chasseloup; Mats Karlsson; Andrew Hooker; Karl Brendel; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacometrics; nonlinear mixed-effects models; misspecification; type I error; power; accuracy; placebo; individual model averaging; IMA; likelihood ratio test; LRT; model averaging; covariate selection; mixture models; visual predictive checks; VPC; avatars; digital twins; virtual individual; Farmaceutisk vetenskap; Pharmaceutical Science;

    Abstract : Pharmacometrics model-based analyses proved to be increasingly useful in drug discovery and development. This usefulness was made evident by the formalisation of the model-integrated drug discovery and development framework (MID3). READ MORE

  6. 4. Volumetric MRI measurements of velocity and flow - Accuracy, visualisation and technical improvements

    Author : Anders Nilsson; Lund Medicinsk strålningsfysik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MRI; 4D flow; phase contrast MRI; velocity mapping;

    Abstract : In the last two decades, phase-contrast magnetic resonance imaging (PC-MRI) has evolved from two-dimensional velocity and flow measurements to volumetric, time-resolved depictions of velocity fields (4D PC). The acquisition of time-resolved velocity fields allows flow visualisations that might provide better understanding of the dynamics of the cardiac system. READ MORE

  7. 5. Society Inhaled. Social Epidemiology of COPD

    Author : Sten Axelsson Fisk; Socialepidemiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Social Epidemiology; Social Medicine; Chronic obstructive pulmonary disease COPD ; Intersectionality; Smoking : epidemiology; Social determinants of health;

    Abstract : Chronic Obstructive Pulmonary Disease (COPD) is a common disease that in its advanced stages is a life-limiting condition and a leading cause of death globally. This thesis aims at increasing the understanding of the socioeconomic disparities that exist both for COPD and its major risk factor, tobacco smoking. READ MORE