Search for dissertations about: "VWD"

Found 5 swedish dissertations containing the word VWD.

  2. 1. Genetic characterization of families with von Willebrand disease

    Author : Elsa Lanke; Malmö Klinisk koagulationsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mutation; bleeding; coagulation; von Willebrand disease; genetics;

    Abstract : von Willebrand disease (VWD) is the most common hereditary bleeding disorder. It is caused by quantitative and/or qualitative defects of the von Willebrand factor (VWF). The severity of the disease can vary considerably, as can the hereditary patterns. READ MORE

  4. 2. von Willebrand disease in women : heavy menstrual bleeding and obstetrical bleeding

    Author : Igor Govorov; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Von Willebrand disease is the most common inherited bleeding disorder worldwide with a prevalence, reaching 1% of general population. vWD is equally distributed between genders. However, vWD-affected females experience specific hemostatic challenges during menstruation and childbirth. READ MORE

  5. 3. Evolution of Transmembrane and Gel-forming Mucins Studied with Bioinformatic Methods

    Author : Tiange Lang; Göteborgs universitet; []
    Keywords : ;

    Abstract : All mucosal membranes of the body are covered by mucus, largely made up of the family of large glycoproteins called mucins. These are instrumental for the protection of the underlying epithelia and involved in the pathogenesis of many diseases in the lungs and the intestine. READ MORE

  6. 4. Thrombin activatable fibrinolysis inhibitor (TAFI) in different hemorrhagic and thrombotic conditions

    Author : Jovan P Antovic; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Thrombin activatable fibrinolysis inhibitor TAFI ; coagulation; fibrinolysis; thrombin; plasmin; factor V Leiden; hemophilia; von Willebrand disease; diabetes mellitus; preeclampsia;

    Abstract : Until recently the coagulation and fibrinolytic systems were usually considered as separate entities. Accounts of a fibrinolysis inhibitor that is generated by thrombin shed more light on this field and changed the concept by giving thrombin, the pivotal enzyme in hemostasis, another important role in the down-regulation of fibrinolysis. READ MORE

  7. 5. The Role of FCGBP in Mucus - Structure, Processing and Function

    Author : Erik Ehrencrona; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mucus; FCGBP; IgG; IBD; COPD; Mucins; Disulphide; GDPH;

    Abstract : In this thesis, a bottom-up approach was used to study the IgG Fc-binding protein (FCGBP), which next to the MUC2 mucin is the second main component of secreted mucus in small intestine and colon. FCGBP is also found in airways during inflammatory conditions with static mucus. READ MORE