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Showing result 1 - 5 of 15 swedish dissertations matching the above criteria.

  2. 1. Evolution of human alpha-herpesviruses

    Author : Peter Norberg; Göteborgs universitet; []
    Keywords : HSV-1; HSV-2; VZV; evolution; recombination; phylogenetic analysis;

    Abstract : Herpesviridae is a large virus family with more than 100 members, which are highly disseminated among animals. Three sub-families have been classified; alpha-herpesviruses, beta-herpesviruses and gamma-herpesviruses. READ MORE

  4. 2. Herpesvirus-induced expression of sLe(x) and related O-linked glycans in the infected cell

    Author : Kristina Nyström; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HSV-1; CMV; VZV; O-linked glycans; Lewis antigens; ICP0;

    Abstract : Lewis antigens constitute a family of fucosylated carbohydrate antigens (glycotopes), involved in leukocyte homing and related immunological phenomena. These glycotopes are only expressed restrictedly in normal cells, but are induced at appropriate occasions. It is well established that many tumors ?hijack? Lewis glycotopes for e.g. READ MORE

  5. 3. Varicella immunity and vaccination

    Author : Anita Svahn; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Varicella-zoster virus (VZV) is an air-borne, extremely contagious herpesvirus. It causes chickenpox, which usually is a benign illness in childhood. Adults, pregnant women and immunocompromised patients often get a severe disease with complications. After infection the virus stays latent in sensory ganglia. READ MORE

  6. 4. Herpesvirus infections in transplant recipients

    Author : Jenny K Lindahl; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Allogeneic stem cell transplantation; Cytomegalovirus; Epstein-Barr virus; Human Herpesvirus type 6; Renal transplantation; Varicella zoster virus;

    Abstract : Abstract Herpesvirus infections are common and can cause serious and life-threatening conditions in transplanted individuals. In this thesis, consisting of 4 papers (I-IV), we investigated primary infection and reactivation of Cytomegalovirus (CMV), Human Herpesvirus type 6 (HHV-6), Varicella Zoster Virus (VZV) and Epstein-Barr Virus (EBV) in transplant patients. READ MORE

  7. 5. Alphaherpesvirus infections of the central nervous system – Biomarkers, diagnostics and antiviral therapy

    Author : Johan Lindström; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; herpesviruses; central nervous system; facial paralysis; cerebrospinal fluid; biomarkers; acyclovir; neurotoxicity; syndromic testing;

    Abstract : Abstract Herpesviruses predate the evolution of humans and are globally ubiquitous. Herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2), and varicella-zoster virus (VZV) establish latency in neuronal tissue and may cause infections in the central nervous system (CNS). READ MORE