Search for dissertations about: "Vaccine failure"

Showing result 1 - 5 of 19 swedish dissertations containing the words Vaccine failure.

  2. 1. The impact of viral vaccines in immunosuppressed and at-risk individuals

    Author : Anja Rosdahl; Torbjörn Norén; Helena Hervius Askling; Sara Cajander; Leonardus (Leo) Visser; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vaccine; Vaccine failure; Immunocompromised host; Hepatitis A; Tick borne encephalitis; SARS-CoV-2; Innate immunity; Adaptive immunity;

    Abstract : Vaccines have saved millions of lives, but for some individuals with a defective immune system the protection may be uncertain. This thesis aims to assess the immune response following viral vaccines in immunocompromised patients and in other groups at-risk. READ MORE

  4. 2. Development of novel DNA vaccine and immunotherapeutic approaches

    Author : Maroof Hasan; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Many potential DNA vaccination and immunotherapeutic strategies has been explored in both animal models and human settings in recent years. However, the failure of efficient and safe method development suggests that it is time to rethink, since more innovative approaches are needed for better control of infection and immunotherapy. READ MORE

  5. 3. Protein based approaches to understand and prevent contagious bovine pleuropneumonia

    Author : Carl Hamsten; Anja Persson; Joachim Frey; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; CBPP; Mycoplasma mycoides subsp. mycoides small colony type; humoral immune responses; recombinant surface proteins; ELISA; subunit vaccine; suspension bead array; Bioengineering; Bioteknik;

    Abstract : Contagious bovine pleuropneumonia (CBPP) is a severe infectious disease caused by Mycoplasma mycoides subsp. mycoides small colony type (M. mycoides SC) and is a vast problem in Africa. READ MORE

  6. 4. Improving immunogenicity of hepatitis B and C viral proteins for vaccine design

    Author : Antony Chen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The hepatitis B and C virus (HBV, HCV) both presents a global health challenge, with an estimated 350 million individuals chronically infected with HBV and over 200 million infected with HCV. Reported cases of HBV and HCV have declined significantly due to screening of blood products and the availability of HBV vaccination. READ MORE

  7. 5. Strategies to enhance the potency of HIV-1 DNA vaccines

    Author : David Hallengärd; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Despite 30 years of intense research on HIV/AIDS, we have yet to arrive at a prophylactic vaccine that confers complete protection. This mission is complicated by the virus’s vast genetic variability and its ability to mask the targets for neutralizing antibodies. READ MORE