Search for dissertations about: "Valproic acid epilepsy"

Found 5 swedish dissertations containing the words Valproic acid epilepsy.

  1. 1. Acquired Epilepsy with a Focus on Stroke: Treatment and Prognosis

    Author : David Larsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; epilepsy; seizure; stroke; cerebrovascular disease; antiseizure medication;

    Abstract : The relationship between epilepsy and stroke is complicated. While stroke is a major cause of epilepsy after middle age, there is also evidence that the risk of stroke is increased in persons with epilepsy. The overall aim of this dissertation is to elaborate on the prognosis and treatment of epilepsy in older adults and its association to stroke. READ MORE

  2. 2. Juvenile myoclonic epilepsy : clinical, genetic, clinical pharmacological, and neurophysiological studies

    Author : Anders Sundqvist; Karolinska Institutet; Karolinska Institutet; []
    Keywords : epilepsy; juvenile myoclonic epilepsy; idiopathic generalised epilepsy; differential diagnosis; genetics; linkage; valproic acid; pharmacokinetics; treatment; drug monitoring; EEG; neurophysiology; neuropsychology. Printed in Sweden by Repro Print; ;

    Abstract : Juvenile myoclonic epilepsy (JME) has been considered to be a discrete phenotype. Evidence from segregation analysis and twin studies suggest that JME is a genetically determined disease, and two previous linkage studies of separately ascertained kindreds have suggested that a JME locus, EJM 1, resides on chromosome 6p close to the HLA region. READ MORE

  3. 3. Sudden unexpected death in epilepsy, incidence, circumstances and risk factors

    Author : Olafur Sveinsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Although Sudden Unexpected Death in Epilepsy (SUDEP) has attracted increasing attention from the scientific community during the last 20 years, important gaps in knowledge still exist that hamper the development of methods aiming at prevention of this, the most devastating consequence of epilepsy. We are still missing large population-based studies on the incidence of SUDEP. READ MORE

  4. 4. Antiepileptic drug utilization : need of sex-specific information and decision support

    Author : Linnéa Karlsson Lind; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Antiepileptic drugs are used for the treatment of epilepsy and for other neurological and psychiatric conditions, and therefore is prescribing of antiepileptic drugs a concern for physicians from many disciplines. The age and sex-specific prevalence, as well as the role of sex and gender aspects, vary between the conditions for which antiepileptic drugs are used. READ MORE

  5. 5. Possibilities of dried blood spots as a matrix in therapeutic drug monitoring of antiepileptic drugs in children

    Author : Camilla Linder; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : For children with epilepsy, therapeutic drug monitoring (TDM) of antiepileptic drugs (AEDs) is essential for treatment. TDM monitoring requires two visits to a health care unit, first for collection of the blood sample before the morning dose and a few days later the family will travel once again to see the pediatrician. READ MORE