Search for dissertations about: "Variations in signature analysis"
Showing result 1 - 5 of 12 swedish dissertations containing the words Variations in signature analysis.
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1. Multimodal applications in medical technology that utilize Raman spectroscopy
Abstract : Biology can often be explained by structures and interactions between molecules. It is therefore of importance for medical sciences that the chemical reactions and molecular compositions of biological samples can be measured. The purpose of this thesis is twofold. READ MORE
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2. Genetic Characterization and Identification of Novel Treatment Targets in Anaplastic Thyroid Carcinoma
Abstract : Anaplastic thyroid cancer (ATC) is a rare and highly aggressive thyroid malignancy, usually resistant to conventional therapeutic strategies. The prognosis of ATC is extremely poor with a median survival rate of 6 months. Current treatment therapy includes surgical resection in combination with external radiotherapy and chemotherapy. READ MORE
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3. Computational Analysis of Tumour Heterogeneity
Abstract : Every tumour is unique and characterised by its genetic, epigenetic, phenotypic, and morphological signature. The diversity observed between and within tumours, and over time, is termed tumour heterogeneity. An increased heterogeneity within a tumour correlates with cancer progression, higher resistance rates, and poorer outcome. READ MORE
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4. Transcriptional Analysis of Cell-Sorted B-cell Lymphomas From High-throughput to Focused Identification of Molecular Targets
Abstract : B cell lymphomas (BCLs) are a group of severe cancers, afflicting both men and women at different ages. Gene expression profiling (GEP), have during the latest decades fundamentally contributed to a better classification and biological understanding of the different BCLs. READ MORE
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5. Global Proteome Survey -Transforming antibody-based affinity proteomics into a global discovery platform
Abstract : Proteomics is expected to generate new insights into biological processes as well as identify novel biomarkers and therapeutic targets since most biological functions are transmitted through proteins. However, due to the complexity displayed by a proteome and inherent limitations associated with current methodologies, proteomic analyses often result in incomplete coverage and inconsistent measurements. READ MORE