Search for dissertations about: "Vascular: drug effects"

Showing result 1 - 5 of 50 swedish dissertations containing the words Vascular: drug effects.

  1. 1. Atherosclerotic Plaque Stability and Vascular Repair

    Author : Anki Knutsson; Kärlväggsbiologi; []
    Keywords : atherosclerosis; diabetes; repair; inflammation; extracellular matrix;

    Abstract : Myocardial infarction and stroke are two of the most common causes of death in the world, mainly caused by a rupture of an atherosclerotic plaque. A vulnerable atherosclerotic plaque is a high-risk plaque that can form a thrombus by rupture. READ MORE

  2. 2. Functional genomics of vascular endothelial cells

    Author : Elisabet Wallgard; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Vasculature; endothelial cells; angiogenesis; vascular endothelial growth factor VEGF ; Notch; transcriptome; genomics; microarray; tumor; retina; morpholino knockdown;

    Abstract : Angiogenesis, the formation of new blood vessels from preexisting ones, is a process involved in normal development as well as in several pathological conditions, such as cancer, ischemic heart disease, wound healing and certain retinal complications. Antiangiogenic targeting is therefore a promising new therapeutic principle. READ MORE

  3. 3. Vascular targeting for enhanced cancer immunotherapy

    Author : Maria Georganaki; Anna Dimberg; Sara Mangsbo; Lena Claesson-Welsh; Wolf Hervé Fridman; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; NATURVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; cancer immunotherapy; tumor vasculature; endothelial activation; IDO1; ELTD1; tertiary lymphoid organ; Biologi; Biology;

    Abstract : Induced angiogenesis and chronic inflammation are major components of tumor immunosuppression. The scope of this thesis is to understand the role of the vasculature in anti-tumor immunity and thereby to improve cancer immunotherapy. READ MORE

  4. 4. MANAGING DRUG USE IN THE ELDERLY. General practitioners’ adherence to guidelines and patients’ conceptions of medication

    Author : Sara Modig; Allmänmedicin och samhällsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Elderly; drug therapy; medication knowledge; beliefs about medicines; adherence; guidelines; renal function; renal risk drugs; cardiovascular disease; GP; primary care;

    Abstract : Introduction: Older patients’ knowledge about their medicines is generally poor. Patients are entitled to be informed on an individual and adequate level. READ MORE

  5. 5. Off-label drug use, medication errors and adverse drug events : among Swedish pediatric inpatients

    Author : Per Nydert; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Abstract : Background: In pediatrics, treatment with drugs is an important and fully integrated part of everyday medical practice. However, authorized drugs specified to be used in children are often lacking which leads to off-label use, i.e. outside of approved product monographs. READ MORE