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Showing result 1 - 5 of 89 swedish dissertations matching the above criteria.

2. 1. Predictors of Dementia : Insulin, Fatty Acids and Vascular Risk Factors

   Author : Elina Rönnemaa; Lena Kilander; Lars Lannfelt; Björn Zethelius; Laura Fratiglioni; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dementia; Alzheimer’s disease; vascular dementia; insulin secretion; diabetes; fatty acids; epidemiology; vascular risk factors; Geriatrics; Geriatrik;

   Abstract : Identification of modifiable risk factors for Alzheimer’s disease (AD) is crucial in order to diminish suffering from this devastating disease. The aim of this thesis was to investigate if different aspects of glucose metabolism, insulin, fatty-acid composition or other vascular risk factors predict the future development of AD and dementia. READ MORE

4. 2. Dementia Proteomics

   Author : Julia Remnestål; Peter Nilsson; Anna Månberg; Pieter Jelle Visser; KTH; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dementia; Proteomics; Alzheimer s disease; Frontotemporal dementia; Antibody array; Suspension bead array; Cerebrospinal fluid; Protein profiling; Biomarker discovery; Bioteknologi; Biotechnology;

   Abstract : The term dementia encompass a number of conditions arising as a consequence of tissue degeneration in the brain. This degeneration is caused by molecular events occurring on a cellular level including inflammation, defective waste disposal and accumulation of insoluble proteins and peptides. READ MORE

5. 3. Biochemical markers in dementia - Exploring Swedish registry data and the human proteome

   Author : Tobias Skillbäck; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomarkers; Dementia; Alzheimer s disease; Vascular dementia; Creutzfeldt Jakob disease; Lewy body dementia; Frontotemporal dementia; Parkinson s disease dementia;

   Abstract : Cerebrospinal fluid (CSF) biomarkers of neurodegenerative diseases have a wide scope of applications in diagnostics, prognosis assessment, disease staging, treatment evaluation and more. In this PhD project we aimed to expand the understanding of the properties of known CSF biomarkers of Alzheimer’s disease (AD) and other neurodegenerative diseases, including the most prevalent dementia disorders. READ MORE

6. 4. Comorbidity and vascular risk factors  associated with idiopathic normal pressure hydrocephalus : the INPH-CRasH Study

   Author : Hanna Israelsson Larsen; Jan Malm; Anders Eklund; Norman Relkin; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hydrocephalus; normal pressure; vascular disease; vascular risk factors; elderly; depression; case control study; epidemiology; dementia; vascular dementia; small vessel disease; cerebrovascular disease; transient ischemic attack; Neurology; neurologi;

   Abstract : Idiopathic normal pressure hydrocephalus (INPH) is a dementia treatable by insertion of a cerebrospinal fluid shunt. It has been suggested that INPH has similar pathophysiological mechanisms as cerebrovascular disease, but the vascular risk factor (VRF) profile of INPH patients has not been assessed using a modern epidemiological approach. READ MORE

7. 5. Alzheimer's disease and vascular dementia in population-based studies

   Author : Mats Ribbe; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; cerebrospinal fluid; dementia; hypertension; magnetic resonance imaging; older; survival; vascular dementia;

   Abstract : Dementia, a clinical syndrome with several profiles and causes, is characterised by a decline in cognitive functions, including memory, learning, executive function, attention, language, and social ability. The most common forms of dementia are Alzheimer’s disease and vascular dementia. READ MORE