Search for dissertations about: "Vascular receptor changes"

Showing result 11 - 15 of 80 swedish dissertations containing the words Vascular receptor changes.

  1. 11. The Human Endometrium : Studies on Angiogenesis and Endometriosis

    Author : Christian Moberg; Matts Olovsson; Anneli Stavreus-Evers; Lalit Kumar Parameswaran Grace; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; endometrium; angiogenesis; endothelial cell; endometriosis; receptivity; implantation; oestrogen receptor; progesterone receptor; crystallin; interleukin; vasoactive intestinal peptide; peritoneal fluid; Obstetrik och gynekologi; Obstetrics and Gynaecology;

    Abstract : Angiogenesis is thought to play a pivotal role in the cycling endometrium. Coordinated by oestrogen and progesterone, endometrial blood vessel development is primarily mediated by vascular endothelial growth factor-A (VEGF-A), which promotes endothelial cell (EC) proliferation and protects ECs from induced apoptosis. READ MORE

  2. 12. Cardiovascular role of PDGF-B in development and disease. Studies in genetically engineered mice

    Author : Henrik Nyström; Göteborgs universitet; []
    Keywords : atherosclerosis; cardiovascular disease; cell retention; in vivo physiology; neointimal hyperplasia; PDGF; transgenic mice; vascular function; vascular smooth muscle cell;

    Abstract : Platelet-derived growth factor B (PDGF-B) is vital for microvascular development, and retention of PDGF-B to extracellular matrix (ECM) is important in this process. However, the role and source of PDGF-B in development of macrovascular function is disputed. READ MORE

  3. 13. Molecular diversity in the Notch receptor family

    Author : Paul Beatus; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : We have studied the Notch family of transmembrane receptors, which play a crucial role in cell fate determination. The Notch signalling pathway represents a conserved mechanism to mediate signalling between adjacent, equivalent cells and to direct them to adopt different cell fates. READ MORE

  4. 14. VEGF-mediated vascular functions in health and disease

    Author : Ziquan Cao; Eric Wahlberg; Yihai Cao; Toste Länne; Kayoko Hosaka; Jack L. Arbiser; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Angiogenesis is essential for physiological processes including embryonic development, tissue regeneration, and reproduction. Under various pathological conditions the same angiogenic process contribute to the onset, development, and progression of many human diseases including cancer, diabetic complications, ocular disease, chronic inflammation and cardiovascular disease. READ MORE

  5. 15. Vascular effects of endothelin in experimental lung injury

    Author : Björn P Persson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : acute lung injury;

    Abstract : Acute lung injury remains a frequent and life threatening consequence of severe sepsis. This thesis has investigated the role of the endothelin (ET) system in sepsis-induced lung injury, with special reference to its effects on two hallmarks of this syndrome - formation of edema and pulmonary hypertension. READ MORE