Search for dissertations about: "Vascular receptor changes"

Showing result 16 - 20 of 80 swedish dissertations containing the words Vascular receptor changes.

  2. 16. Dynamics of Ca2 handling in vascular smooth muscle

    Author : Karl Dreja; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; smooth muscle; phenotypic modulation; caveolae; Physiology; confocal microscopy; calcium; Fysiologi;

    Abstract : Intracellular Ca2+ is a key regulator of vascular contractility, and thereby of blood perfusion and pressure. Ca2+ signals are essential also for cell migration, proliferation and regulation of numerous enzymes. READ MORE

  4. 17. The role of proprotein convertases in vascular disease

    Author : Bianca E Suur; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : To date, the role of the proprotein convertase subtilisin/kexin (PCSK) family in vascular disease is largely unknown, with the exception of PCSK9 and its key function in lipid metabolism. The PCSK family constitutes of 9 different proteases, of which the first 7 show remarkable structural and functional overlap. READ MORE

  5. 18. Sensory neuropeptides and nitric oxide in nasal vascular regulation

    Author : Johan Rinder; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Sensory nerves; neuropeptides; nasal mucosa; nitric oxide; vascular regulation; acoustic rhinometry; NK1-receptors; CGRP-receptors; vanilloid receptors; capsaicin; lactic acid; exercise; a-adrenoceptor agonists; pig; human.;

    Abstract : The role of sensory neuropeptides and nitric oxide in vascular regulation was investigated in the pig nasal mucosa in vivo using arterial blood flow measurements and acoustic rhinometry for analysis of capacitance function. Moreover, the effects of heavy physical exercise, a-adrenoceptor agonists, nitric oxide synthase (NOS) inhibition, L-arginine, nitric oxide (NO) gas, histamine and capsaicin on nasal cavity NO levels and nasal cavity volume, were investigated in healthy subjects. READ MORE

  6. 19. Functions of Pericytes in Ischemic Stroke

    Author : Michaela Roth; Lund Neurologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Stroke; Pericytes; RGS5; Blood-brain barrier; vascular remodelling; scar formation;

    Abstract : Ischemic stroke remains one of the leading causes of death and disability worldwide, and its burden is predicted to further increase due to the aging population. The only available treatments, thrombolysis or thrombectomy, can only be applied within a limited time window after stroke onset, and thus are applicable only to a small proportion of stroke patients. READ MORE

  7. 20. Sleep disordered breathing and hemodynamic function

    Author : Ludger Grote; Göteborgs universitet; []
    Keywords : sleep apnea; hypertension; blood pressure; vascular function; exercise; arousal;

    Abstract : This thesis addresses the association between sleep disordered breathing (SDB) and hemodynamic function. A cross sectional study in a sleep laboratory cohort (n=1190) demonstrated a dose-response relationship between the severity of SDB, expressed as respiratory disturbance index (RDI), and office blood pressure, heart rate, and the risk of hypertension. READ MORE