Search for dissertations about: "Vascular smooth muscle cells"

Showing result 21 - 25 of 162 swedish dissertations containing the words Vascular smooth muscle cells.

  2. 21. On cellular sources for intimal hyperplasia after vascular interventions

    Author : Stefan Mellander; Göteborgs universitet; []
    Keywords : intimal hyperplasia; vascular intervention; smooth muscle cell; blood-born mononuclear cell; prosthetic graft; balloon injury; pig; rabbit;

    Abstract : Vascular interventions for the treatment of symptomatic atherosclerosis fail in up to 40 % of the cases during the first year. One important reason is the development of a narrowing process known as intimal hyperplasia (IH). The cells forming IH resemble smooth muscle cells (SMCs) from the media of the arterial wall. READ MORE

  4. 22. Vascular progenitor cells in arterial remodeling

    Author : Monika K Grudzinska; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cardiovascular disease is the leading cause of global mortality and physical disability mainly due to the complications such as myocardial infarction or stroke. Physiological healing reaction takes place in the diseased vessel wall aimed to repair the vessel after an injury. READ MORE

  5. 23. Regulation of vascular function by fluid mechanical forces. Development of a new vascular experimental platform for integrative physiological and molecular biological studies of living conduit vessels

    Author : Li-Ming Gan; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; perfusion model; endothelium; smooth muscle cells; shear stress; pressure; nitric oxide; endothelin-1; vascular endothelial growth factor; c-jun; c-fos; real-time PCR; NO probe.;

    Abstract : The vascular endothelium is a multifunctional interface between blood flow and target organs and is continuously exposed to fluid mechanical forces such as shear stress, compressive, and tensile forces. Both in vivo and in vitro data indicate that biomechanical forces exert important modulating effects on key vascular functions. READ MORE

  6. 24. Regulation of gene expression in the vascular wall

    Author : Erik Larsson; Göteborgs universitet; []
    Keywords : smooth muscle; endothelium; angiogenesis; SRF; myocardin; LPP; gene regulation; genetics; microRNA;

    Abstract : Blood vessel growth and function are closely related to a number of pathological conditions, including tumor angiogenesis, wound healing and atherosclerosis. Smooth muscle cells (SMC) and endothelial cells (EC), the two major constituents of the vascular wall, are both characterized by the expression of unique phenotypic marker genes, many of which have vital roles in blood vessel development and disease. READ MORE

  7. 25. Studies on extracellular matrix proteins in vascular disease

    Author : Åsa Ström; Kärlväggsbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kardiovaskulära systemet; Cardiovascular system; smooth muscle cells; osteopontin; extracellular matrix; atherosclerosis;

    Abstract : The composition of the vascular extracellular matrix (ECM) is altered during remodeling conditions such as atherosclerosis. The changed ECM regulates events that are important for the progression of disease including smooth muscle cell (SMC) behaviour and collagen fiber formation. READ MORE