Search for dissertations about: "Vasili Hauryliuk"
Found 3 swedish dissertations containing the words Vasili Hauryliuk.
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1. A Few Strokes to the Family Portrait of Translational GTPases
Abstract : Protein biosynthesis is a core process in all living organisms. Assembly of the protein chain from aminoacids is catalysed by the ribosome, ancient and extremely complex macromolecular machine. READ MORE
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2. Functional studies of Escherichia coli stringent response factor RelA
Abstract : RelA is a ribosome associated multi-domain enzyme, which plays a crucial role in adaptation ofEscherichia coli to nutritional stress as such as amino acid deficiency. It detects the deficiency of aminoacids in the cell by monitoring whether a tRNA at the acceptor site (A-site) of the ribosome is chargedwith amino acid or not. READ MORE
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3. Novel RelA-SpoT Homolog toxin-antitoxin systems that inhibit bacterial growth through production of toxic alarmone ppApp
Abstract : The stress alarmone nucleotides guanosine pentaphosphate (pppGpp) and tetraphosphate (ppGpp), collectively known as (p)ppGpp, are the molecular mediators of the bacterial stringent response — a bacterial stress response implicated in virulence, antibiotic tolerance and biofilm formation. At high concentrations, (p)ppGpp halts bacterial growth, inhibits protein synthesis and rewires transcription and metabolism. READ MORE