Search for dissertations about: "Venerology"

Showing result 11 - 15 of 93 swedish dissertations containing the word Venerology.

2. 11. Psoriasis in Sweden : observational studies from an epidemiological perspective

   Author : David Hägg; Marcus Schmitt-Egenolf; Anders Sundström; Marie Eriksson; Bernt Lindelöf; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Psoriasis; Systemic treatments; Biologic treatments; PASI; DLQI; Register-based research; Dermatology and Venerology; dermatologi och venereologi;

   Abstract : Background: Psoriasis is a heterogeneous disease with several clinical manifestations; the symptoms are characterized by redness, scaliness and thickness of the skin. There are several treatment options available for psoriasis and patients with moderate to severe psoriasis generally need systemic agents. READ MORE

4. 12. Cutaneous melanoma in children and adolescents and aspects of naevus phenotype in melanoma risk assessment

   Author : Pia Karlsson; Inger Rosdahl; Johan Hansson; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; melanoma; naevus; childhood; adolescence; prevention; epidemiology; Dermatology and venerology; Dermatologi och venerologi;

   Abstract : Cutaneous malignant melanoma (CMM) is one of the most rapidly increasing cancers in the Swedish population. The aetiology of melanoma is a complex interplay between genetics, host characteristics and environmental factors. READ MORE

5. 13. Studies on Vitamin A Signaling in Psoriasis : A Comparison Between Normal and Lesional Keratinocytes

   Author : Teresa Karlsson; Jan Öivind Moskaug; Uppsala universitet; []
   Keywords : Medical sciences; Psoriasis; vitamin A; retinoids; retinoid receptor; differentiation; keratinocyte; skin; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Dermatology and Venerology; dermatologi och venereologi;

   Abstract : Vitamin A and metabolites (retinoids) are crucial for normal epidermal maturation. Physiological effects are mediated by retinoic acid (RA) that activates nuclear retinoic acid receptors (RARs) in complexes with retinoid X receptors (RXRs), resulting in altered gene transcription.Psoriasis is a common disease with unknown etiology. READ MORE

6. 14. Vitiligo and Piebaldism : Treatmant of Leucoderma by Transplantation of autologous melanocytes

   Author : Mats J. Olsson; Hugh Zachariae; Uppsala universitet; []
   Keywords : Medical sciences; leucoderma; leukoderma; vitiligo; piebaldism; melanocytes; pigmentation; cell culturing; serum-free; transplantation; surgery; autoimmune disease; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Dermatology and Venerology; dermatologi och venereologi;

   Abstract : Background: Vitiligo and piebaldism are disorders in which the affected skin lack epidermal melanocytes. Vitiligo is acquired and can clinically be subgrouped, but the aetiology is still not fully understood. The most common type, generalized vitiligo (vitiligo vulgaris) has autoimmune involvement and affects about 1. READ MORE

7. 15. Retinoic Acid Metabolism Blocking Agents and the Skin : In vivo and in vitro Studies of the Effects on Normal and Diseased Human Epidermis

   Author : Elizabeth Pavez Loriè; Anders Vahlquist; Hans Törmä; Marie Virtanen; Helen Håkansson; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CYP; CYP26; retinoids; vitamin A; RAMBA; metabolism; keratinocyte; epidermis; retinoid regulated genes; Dermatology and venerology; Dermatologi och venerologi;

   Abstract : Retinoic Acid Metabolism Blocking Agents (RAMBAs) increase the endogenous levels of all-trans retinoic acid (RA) by inhibiting CYP26 enzymes. Thus they are believed to mimic the effects of retinoid treatment. Their mechanism of action and effects on vitamin A metabolism in keratinocytes are however uncertain. READ MORE