Search for dissertations about: "Venkateswara Rao Jonna"

Found 1 swedish dissertation containing the words Venkateswara Rao Jonna.

  1. 1. Class I Ribonucleotide Reductases : overall activity regulation, oligomerization, and drug targeting

    Author : Venkateswara Rao Jonna; Anders Hofer; Arne Holmgren; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Ribonucleotide reductase; GEMMA; Allosteric regulation; medicinsk biokemi; Medical Biochemistry;

    Abstract : Ribonucleotide reductase (RNR) is a key enzyme in the de novo biosynthesis and homeostatic maintenance of all four DNA building blocks by being able to make deoxyribonucleotides from the corresponding ribonucleotides. It is important for the cell to control the production of a balanced supply of the dNTPs to minimize misincorporations in DNA. READ MORE