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Showing result 1 - 5 of 12 swedish dissertations matching the above criteria.

  1. 1. Characterization of specific domains of the cellulose and chitin synthases from pathogenic oomycetes

    Author : Christian Brown; Vincent Bulone; Carol Munro; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cellulose biosynthesis; chitin biosynthesis; cellulose synthase genes; chitin synthase genes; oomycetes; Saprolegnia monoica; Microtubule Interacting and Trafficking MIT domain; Pleckstrin Homology PH domain; Biotechnology; Bioteknologi;

    Abstract : Some oomycetes species are severe pathogens of fish or crops. As such, they are responsible for important losses in the aquaculture industry as well as in agriculture. Saprolegnia parasitica is a major concern in aquaculture as there is currently no method available for controlling the diseases caused by this microorganism. READ MORE

  2. 2. Analysis of sterol metabolism in the pathogenic oomycetes Saprolegnia parasitica and Phytophthora infestans

    Author : Paul Dahlin; Vincent Bulone; Lisbeth Jonsson; Katharina Pawlowski; Lauren Mckee; Sophia Ekengren; Folke Sitbon; Steven Kelly; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Plant Physiology; växtfysiologi;

    Abstract : The primary objective of this thesis was to investigate the sterol metabolism of two pathogenic oomycetes, specifically the processes of sterol synthesis and sterol acquisition in the fish pathogen Saprolegnia parasitica (Saprolegniales) and the plant pathogen Phytophthora infestans (Peronosporales). Furthermore, the effects of steroidal glycoalkaloids from Solanaceous plants, on P. READ MORE

  3. 3. Cellulose Biosynthesis in Oomycetes

    Author : Johanna Fugelstad; Vincent Bulone; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; cellulose biosynthesis; cellulose synthase genes; Oomycetes; Phytophthora infestans; Saprolegnia monoica.; Other bioengineering; Övrig bioteknik;

    Abstract : Oomycetes have long been considered as a separate class within the kingdom Fungi, but they are in fact closer to brown algae. They are currently classified in the Stramenopile eukaryotic kingdom, which includes heterokont algae and water molds. READ MORE

  4. 4. Functional characterization of cellulose and chitin synthase genes in Oomycetes

    Author : Johanna Fugelstad; Vincent Bulone; Carol Munro; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; cellulose biosynthesis; chitin biosynthesis; cellulose synthase gene; chitin synthase gene; Oomycetes; Phytophthora infestans; Saprolegnia monoica; pleckstrin homology domain; Microbiology; Mikrobiologi;

    Abstract : Some species of Oomycetes are well studied pathogens that cause considerable economical losses in the agriculture and aquaculture industries. Currently, there are no chemicals available that are environmentally friendly and at the same time efficient Oomycete inhibitors. READ MORE

  5. 5. Theoretical Studies of Protein-Ligand Interactions

    Author : Kuang Guanglin; Tu Yaoquan; Bulone Vincent; David van der Spoel; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Binding free energy; molecular dynamics; molecular docking; metadynamics; nicotinic receptor; amyloid fibril; PH domain; Theoretical Chemistry and Biology; Teoretisk kemi och biologi;

    Abstract : The protein-ligand interaction is an important issue in rational drug design and protein function research. This thesis focuses on the study of protein-ligand interactions using various molecular modeling methods, which are used in combination to predict the binding modes and calculate the binding free energies of several important protein-ligand systems, as summarized below. READ MORE