Search for dissertations about: "Viral Evolution"

Showing result 1 - 5 of 70 swedish dissertations containing the words Viral Evolution.

  2. 1. Influenza A Virus : Spatial analysis of influenza genome trafficking and the evolution of the neuraminidase protein

    Author : Dan Dou; Robert Daniels; Martin Schwemmle; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Influenza A virus; IAV; neuraminidase; NA; IAV genome trafficking; viral entry; viral replication; co-infection; antigenic drift; antigenic shift; NA assembly; transmembrane domain; evolution; Biochemistry; biokemi;

    Abstract : Influenza A viruses (IAVs) are a common infectious agent that seasonally circulates within the human population that causes mild to severe acute respiratory infections. The severity of the infection is often related to how the virus has evolved with respect to the pre-existing immunity in the population. READ MORE

  4. 2. Influenza neuraminidase assembly : Evolution of domain cooperativity

    Author : Diogo da Silveira Vieira da Silva; Robert Daniels; Ron Fouchier; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Influenza; neuraminidase; assembly; transmembrane domain; evolution; Biochemistry; biokemi;

    Abstract : Influenza A virus (IAV) is one of the most common viruses circulating in the human population and is responsible for seasonal epidemics that affect millions of individuals worldwide. The need to develop new drugs and vaccines against IAVs led scientists to study the main IAV surface antigens hemagglutinin (HA) and neuraminidase (NA). READ MORE

  5. 3. Exploring the diversity and evolution of giant viruses in deep sea sediments using genome-resolved metagenomics

    Author : Disa Bäckström; Thijs J. G. Ettema; Anna J. Szekely; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Metagenomics; binning; viruses; NCLDV; Megavirales; viral evolution.;

    Abstract : Viruses are the most abundant biological entities on this planet, which is impressive considering that they are completely dependent on their hosts for reproduction. Recently the idea of what viruses are has changed dramatically, with the discovery of giant viruses that belong to the Nucleocytoplasmic Large DNA Viruses (NCLDV), such as Mimiviridae, Marseilleviridae, and the proposed families Pandoraviruses, and Pithoviruses. READ MORE

  6. 4. Evolution and viral mimicry of short linear motif-mediated interactions

    Author : Filip Mihalič; Per Jemth; Leo James; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; phage display; protein-protein interactions; large-scale discovery; short linear motifs; viral mimcry; viral hijacking; Biokemi; Biochemistry; Medical Biochemistry; Medicinsk biokemi;

    Abstract : Proteins are one of the most fundamental building blocks of life and their interactions regulate every cellular process. Historically they have been conceptualized as predominantly folded entities with well-defined secondary and tertiary structures. READ MORE

  7. 5. Evolution of human alpha-herpesviruses

    Author : Peter Norberg; Göteborgs universitet; []
    Keywords : HSV-1; HSV-2; VZV; evolution; recombination; phylogenetic analysis;

    Abstract : Herpesviridae is a large virus family with more than 100 members, which are highly disseminated among animals. Three sub-families have been classified; alpha-herpesviruses, beta-herpesviruses and gamma-herpesviruses. READ MORE