Search for dissertations about: "Virus Activation"

Showing result 1 - 5 of 251 swedish dissertations containing the words Virus Activation.

  2. 1. Fusion activation in murine leukemia virus

    Author : Michael Wallin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MLV; retrovirus; virus entry; membrane fusion; disulphide isomerization;

    Abstract : This thesis describes the fusion activation in Murine leukaemia virus (MLV). During entry of retroviruses into uninfected cells, the viral and cellular membranes fuse. The fusion process is mediated by the viral envelope protein composed of three SU and TM heterodimers. READ MORE

  4. 2. Activation, adhesion and motility of B lymphocytes in health and disease

    Author : Natalija Gerasimcik; Eva Severinson; Victor Tybulewicz; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; B cells; activation; motility; IL-4; EBV; Dock10; Cdc42; Rac1 and Rac2; immunologi; Immunology;

    Abstract : B cells can be activated by T cell-dependent stimuli, such as CD40 ligation and cytokines, which induce extensive proliferation, class switch recombination and somatic hypermutation.Epstein-Barr virus (EBV) can also induce B cell activation by mimicking T cell help through its main oncoprotein, latent membrane protein 1 (LMP-1). READ MORE

  5. 3. Exploring the Molecular Dynamics of Proteins and Viruses

    Author : Daniel Larsson; David van der Spoel; Modesto Orozco; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; molecular dynamics; virus dynamics; capsid dissolution; satellite tobacco necrosis virus; satellite tobacco mosaic virus; virus genome structure; gas phase protein structure; water layer; micelle embedded protein; membrane protein; Chemistry with specialization in Biophysics; Kemi med inriktning mot biofysik;

    Abstract : Knowledge about structure and dynamics of the important biological macromolecules — proteins, nucleic acids, lipids and sugars — helps to understand their function. Atomic-resolution structures of macromolecules are routinely captured with X-ray crystallography and other techniques. READ MORE

  6. 4. Activation of Herpes simplex virus type 1 origin of DNA replication

    Author : Alireza Aslani; Göteborgs universitet; []
    Keywords : DNA replication; Herpes simplex virus; helicase; UL9; OBP; ICP8; ATP; oriS; hairpin;

    Abstract : Herpes simplex virus type 1 has been used to study the molecular mechanism of DNA replication. Initiation of DNA replication takes place at specific regions called origins of replication. The HSV-1 genome contains three origins of replication, one copy of oriL and two copies of oriS. READ MORE

  7. 5. The role of non-coding single-stranded oligonucleotides on Respiratory syncytial virus infection

    Author : Sandra Axberg Pålsson; Anna-Lena Spetz; Annika Karlsson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Respiratory syncytial virus RSV ; single-stranded oligonucleotide ssON ; small non-coding RNA sncRNA ; nucleolin; virus infection; antiviral; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Respiratory syncytial virus (RSV) is an enveloped RNA virus of the Pneumoviridae family. RSV is reported to infect host cells by receptor-mediated endocytosis, also called clathrin-dependent endocytosis. Many reports indicate that the virus utilizes the host receptor nucleolin for entry. READ MORE