Search for dissertations about: "Visual DNA"

Showing result 1 - 5 of 24 swedish dissertations containing the words Visual DNA.

2. 1. Advances in DNA Detection

   Author : Yajing Song; Olof Emanuelsson; Jonas Tegenfeldt; KTH; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; DNA detection; active filter paper; visual detection; throughput; fluorescence; superparamagnetic beads; rare DNA; Q-PCR; chemical fragmentation; DNA library preparation; massively parallel sequencing; SRA - Molecular Bioscience; SRA - Molekylär biovetenskap;

   Abstract : DNA detection technologies have an increasing importance in our everyday lives, with applications ranging from microbial diagnostics to forensic analysis, food safety evaluation, and environmental monitoring. Currently, as the associated costs decrease, DNA diagnostic techniques are routinely used in research laboratories, in clinical and forensic practice. READ MORE

4. 2. Visual and magnetic detection of antimicrobial resistance genes using nanoparticles and isothermal amplification

   Author : Darío Sánchez Martín; Teresa Zardán Gómez de la Torre; Maria Strömme; Mahiar Hamedi; Uppsala universitet; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; DNA amplification; isothermal amplification; visual detection; nanoparticles; VAM-NDA; rolling circle amplification; phi29 DNA polymerase; padlock probes.; Teknisk fysik med inriktning mot nanoteknologi och funktionella material; Engineering Science with specialization in Nanotechnology and Functional Materials;

   Abstract : Antibiotic resistance is becoming an increasing concern, necessitating new ways to diagnose and treat it rapidly and accurately. One proposed solution is the use of nucleic acid amplification tests, capable of detecting resistance in just a few hours, as opposed to the several days that traditional testing methods may require. READ MORE

5. 3. Charged Polymers: From DNA to Polyampholytes

   Author : Malek O Khan; Beräkningskemi; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; computational steering; DNA condensation; ion correlations; electrostatic interactions; colloidal stability; polyampholytes; Monte Carlo simulations; polyelectrolytes; Theoretical chemistry; quantum chemistry; Teoretisk kemi; kvantkemi;

   Abstract : Three main themes are outlined in this thesis: Polyelectrolytes/DNA : In a living cell, DNA molecules have a compact conformation in order to fit in, while in a test tube they will take on an expanded cylindrical shape, due to the negative phosphate groups along the DNA molecule. With the help of computer simulations it has been shown that like-charged monomers of a poly- electrolyte can attract each other if the counterions are taken into account. READ MORE

6. 4. Methods for Analyzing Genomes

   Author : Patrik L. Ståhl; Joakim Lundeberg; Ivo Gut; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; array; sequence capture; genotyping; trinucleotide threading; sequencing; massively parallel sequencing; single molecule sequencing; Visual DNA; p53; single nucleotide polymorphism; biomarker; Genetics; Genetik;

   Abstract : The human genome reference sequence has given us a two‐dimensional blueprint of our inherited code of life, but we need to employ modern‐day technology to expand our knowledge into a third dimension. Inter‐individual and intra‐individual variation has been shown to be larger than anticipated, and the mode of genetic regulation more complex. READ MORE

7. 5. DNA Tools and Microfluidic Systems for Molecular Analysis

   Author : Jonas Jarvius; Ulf Landegren; Mats Nilsson; P Luke Lee; Uppsala universitet; []
   Keywords : Molecular medicine; Proximity ligation; Microfluidics; Single molecule detection; Microarray; Bonding; Molekylärmedicin;

   Abstract : Improved methods are needed to interrogate the genome and the proteome. Methods with high selectivity, wide dynamic range, and excellent precision, capable of simultaneously analyzing many biomolecules are required to decipher cellular function. This thesis describes a molecular and microfluidic toolbox designed with those criteria in mind. READ MORE