Search for dissertations about: "Vitamin B12 and folate"

Showing result 1 - 5 of 23 swedish dissertations containing the words Vitamin B12 and folate.

2. 1. Studies on Vitamin B12 and Folate Deficiency Markers in the Elderly : A Population-based Study

   Author : Karin Björkegren; Kurt Svärdsudd; Åke Schwan; Herman Nilsson-Ehle; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Cobalamin; folate; MMA; tHcy; multivitamin; symptoms; survey; treatment trial; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; Family Medicine; Allmänmedicin;

   Abstract : The aims of this study were to document the levels of cobalamin, folate, methylmalonic acid (MMA) and total homocysteine (tHcy) in serum and their relations to symptoms, clinical findings, and other factors in order to improve the possibilities of detecting early deficiency of vitamin B12 or folate, and to study the effects of cobalamin and folic acid treatment over a three-year period. The study population consisted of a 20% random sample of persons 70 years or older living in Älvkarleby in mid-Sweden. READ MORE

4. 2. The CpG island methylator phenotype in colorectal cancer : studies on risk and prognosis

   Author : Anna Dahlin; Richard Palmqvist; Bethany van Guelpen; Maria Henriksson; Åke Öberg; Xiao-Feng Sun; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal cancer; DNA methylation; folate; microsatellite instability MSI ; prognosis; risk factors; t-lymphocytes; the CpG island methylator phenotype CIMP ; Vitamin B12; Pathology; Patologi; Tumour biology; Tumörbiologi; patologi; Pathology;

   Abstract : Background Colorectal cancer (CRC) is the second most common malignancy in developed countries. The mortality is high, with nearly half of patients dying from the disease. The primary treatment of CRC is surgery, and decisions about additional treatment with chemotherapy are based mainly on tumor stage. READ MORE

5. 3. Vascular mechanisms in dementia with special reference to folate and fibrinolysis

   Author : Nils-Olof Hagnelius; Torbjörn K. Nilsson; Teodoro Bottiglieri; Örebro universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dementia; Alzheimer’s disease; vascular dementia; folate; homocysteine; vitamin B12; CSF Serum folate ratio; fibrinolysis; tPA; PAI-1; Geriatrics and medical gerontology; Geriatrik och medicinsk gerontologi; MEDICINE; MEDICIN; Geriatrik; Geriatrics; Medicin; Medicine;

   Abstract : The aim of this thesis was to study the biomarker homocysteine and other novel potential vascular risk factors for dementia. In an out-patient based study of a cohort of 926 consecutive subjects referred to our Memory Unit during 1996―2000, serum-folate was lower and total plasma homocysteine (tHcy) and serum methyl malonate were higher in subjects being prescribed with B12. READ MORE

6. 4. Cobalamin communication in Sweden 1990 – 2000 : views, knowledge and practice among Swedish physicians

   Author : Mats Nilsson; Johan Lökk; Göran Westman; Bo Norberg; Kurt Svärdsudd; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Cobalamin; folate; iron; homocysteine; MMA; vitamin B12 deficiency; therapy tradition; drug epidemiology; communication; receivers; senders; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; medicin; Medicine;

   Abstract : Cobalamin (vitamin B12) is one of several essential micronutrients needed by the human organism. Other important micronutritients, which interplay with vitamin B12, are folate and iron. During the last ten years, the attention has been drawn to different forms of neurological disorders supposed to be caused by vitamin B12 deficiency. READ MORE

7. 5. Vitamin B12 and folate depletion in the elderly. Diagnosis, clinical correlates and causes

   Author : Catharina Lewerin; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; aged; methylmalonic acid; homocysteine; vitamin B12; folic acid; renal function; cognition; movement; atrophic gastritis;

   Abstract : Subclinical vitamin B12 and folate deficiency is common in the elderly. The clinical significance remains unresolved. There is not a universally accepted set of laboratory criteria for diagnosis, however subclinical deficiency is important to diagnose since it is easy to treat. READ MORE