Search for dissertations about: "Vitamin D analysis"

Showing result 1 - 5 of 42 swedish dissertations containing the words Vitamin D analysis.

  1. 1. Regulation of Vitamin D 25-hydroxylases : Effects of Vitamin D Metabolites and Pharmaceutical Compounds on the Bioactivation of Vitamin D

    Author : Maria Ellfolk; Kjell Wikvall; Maria Norlin; Olavi Pelkonen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CYP2D25; vitamin D 25-hydroxylase; transcriptional regulation; vitamin D; CYP2R1; CYP2J2; CYP27A1; phenobarbital; efavirenz; fibroblast; LNCaP; Pharmaceutical biochemistry; Farmaceutisk biokemi;

    Abstract : A 700bp portion of the promoter of CYP2D25, the porcine microsomal vitamin D 25-hydroxylase was isolated and sequenced. The computer analysis of the sequence revealed the existence of a putative VDRE at 220 bp upstream of the transcription start site. READ MORE

  2. 2. Epidemiological aspects of drug-related vitamin D deficiency and osteoporotic fractures

    Author : Ola Nordqvist; Martin Carlsson; Pär Wanby; Thomas Neumark; Björn Wettermark; Linnéuniversitetet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vitamin D; secondary osteoporosis; fractures; drug risk management; medical guideline adherence; electronic health records; real-world data; risk assessment; awareness; attitudes; personalised medicine; cross-sectional study; cohort study; qualitative analysis; thematic analysis; pharmacoepidemiology; Biomedical Sciences; Biomedicinsk vetenskap;

    Abstract : Background: Vitamin D deficiency, secondary osteoporosis and low-energy fractures (LEF) as side effects of specific drugs were first described more than half a century ago. These effects are recognized in guidelines where patients prescribed risk drugs are recommended follow-up with testing and supplementation. READ MORE

  3. 3. Vitamin D and its receptor in parathyroid tumors

    Author : Pamela Correa; Martin Bäckdahl; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; hyperparathyroidism; loss of heterozygoisty; vitamin D; vitamin D receptor; polymorphism; hydroxylase; genetics; tumorigenesis; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

    Abstract : Correa, P. 2002. Vitamin D and its receptor in parathyroid tumors. Acta Universitatis Upsaliensis. READ MORE

  4. 4. Vitamin D and blood pressure

    Author : Ann Burgaz; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The physiological function of circulating 25-hydroxyvitamin D (25(OH)D) is to maintain serum calcium range that supports skeletal system. Evidence is mounting that vitamin D has beneficial effects on other important functions in tissues not primarily related to mineral metabolism. READ MORE

  5. 5. Vitamin A and Osteoporosis : Experimental and Clinical Studies

    Author : Sara Johansson; Håkan Melhus; Andreas Kindmark; Monica Lind; Göran Toss; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Internal medicine; vitamin A; bone; osteoporosis; Invärtesmedicin; Internal medicine; Invärtesmedicin;

    Abstract : Vitamin A in high doses is severely toxic to the rat skeleton, and the active metabolite retinoic acid (RA) can induce bone resorption in vitro. An excessive dietary intake of vitamin A has been associated with reduced bone mineral density and an increased risk of hip fracture. READ MORE