Search for dissertations about: "WNT7A"

Showing result 1 - 5 of 8 swedish dissertations containing the word WNT7A.

  1. 1. Molecular Genetic Studies of Sporadic and MEN1-Associated Endocrine Pancreatic Tumors

    Author : Daniel Lindberg; Gunnar Westin; Göran Åkerström; Bo Wängberg; Uppsala universitet; []
    Keywords : Surgery; pancreatic endocrine tumor; MEN1; LOH; WNT7A; HDAC11; CDK4; CDKN2B p15; CDKN1B p27; CDKN2C p18; c-Myc; Smad4; pyrosequencing; epigenetic; methylation; tumor suppressor; Kirurgi;

    Abstract : Pancreatic endocrine tumors (PETs) may cause typical syndromes of hormone excess, or appear clinically non-functioning without hormonal symptoms. PETs occur sporadically, in association with the multiple endocrine neoplasia type 1 (MEN1) syndrome, or rarely the von Hippel-Lindau syndrome. READ MORE

  2. 2. Wnt signaling affects cell adhesion and neuronal differentiation

    Author : Maria Lindqvist; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The mammalian central nervous system (CNS) consists of the brain and the spinal cord. The entire CNS is derived from the walls of a fluid-filled neural tube that is formed at an early stage of embryonic development. The tube itself becomes the adult ventricular system. READ MORE

  3. 3. Biomarkers in nasopharyngeal carcinoma

    Author : Zi-Ming Du; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Nasopharyngeal carcinoma (NPC) is one of the most common malignancies in certain areas of Southern China, Southeastern Asia and Northern Africa. Currently, evaluation of NPC prognosis is mainly based on the tumor-node-metastasis (TNM) staging system. READ MORE

  4. 4. Wnt signaling in early brain development and disease

    Author : Panagiotis Papachristou; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Wnt/Planar Cell Polarity (PCP) signaling is involved in many cellular processes throughout the development of the embryo. These include control of proliferation, differentiation, migration and cell fate decisions. Deregulation of Wnt/PCP signaling can lead to many developmental abnormalities and cancer. READ MORE

  5. 5. Early function of KCC2 and Wnt genes : cytoskeletal effects in neural stem cells

    Author : Zachi Horn; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : From closure of the neural tube until formation of neuronal networks, cells undergo several crucial changes which depend on the expression of many important molecules. GABA, the principal inhibitory neurotransmitter in the adult nervous system, acts as an excitatory signal during embryonic development. READ MORE