Search for dissertations about: "Wanjin Tang"

Found 1 swedish dissertation containing the words Wanjin Tang.

2. 1. Hormonal Regulation of the Human CYP27A1 and CYP7B1 Genes

   Author : Wanjin Tang; Kjell Wikvall; Maria Norlin; Mats Gåfvels; Uppsala universitet; []
   Keywords : Pharmaceutical biochemistry; CYP27A1; CYP7B1; cholesterol; estrogen; androgen; prostate; glucocorticoid receptor; fetal development; Farmaceutisk biokemi;

   Abstract : CYP27A1 and CYP7B1 are widely expressed in various human tissues and are two key enzymes involved in the pathways for conversion of cholesterol to bile acids. Also, CYP27A1 is involved in bioactivation of vitamin D3 and CYP7B1 plays a role in 7alpha-hydroxylation of dehydroepiandrosterone and other steroids. READ MORE