Search for dissertations about: "Water Maze"

Showing result 1 - 5 of 39 swedish dissertations containing the words Water Maze.

  2. 1. Growth hormone in the brain : Focus on cognitive function

    Author : Erika Brolin; Fred Nyberg; Mathias Hallberg; Alfhild Grönbladh; Jörgen Isgaard; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Growth hormone; central nervous system; cognition; morphine; gamma-hydroxybutyrate; diabetes; Barnes maze; Morris water maze; mice; rats; Pharmaceutical Science; Farmaceutisk vetenskap;

    Abstract : Cognitive impairments are an increasing health problem worldwide. In the developed countries, the average life expectancy has dramatically increased over the last decades, and with an elderly population more cases of cognitive impairments appear. READ MORE

  4. 2. Growth Hormone and Anabolic Androgenic Steroids : Effects on Neurochemistry and Cognition

    Author : Alfhild Grönbladh; Mathias Hallberg; Jörgen Isgaard; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Growth hormone; anabolic androgenic steroids; nandrolone decanoate; insulin-like growth factor; GABAB; opioids; memory; water maze; autoradiography; central nervous system; rats; Biological Research on Drug Dependence; Biologisk beroendeforskning;

    Abstract : Growth hormone (GH) stimulates growth and metabolism but also displays profound effects on the central nervous system (CNS). GH affects neurogenesis and neuroprotection, and has been shown to counteract drug-induced apoptosis in the brain. READ MORE

  5. 3. The Impact of Growth Hormone and Gamma-Hydroxybutyrate (GHB) on Systems Related to Cognition

    Author : Jenny Johansson; Mathias Hallberg; Fred Nyberg; Linda Fryklund; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Growth Hormone; Gamma-Hydroxybutyrate; GABAB; Opioids; Insulin-like growth factor 1; Rats; Central Nervous System; Autoradiography; Radioimmunoassay; ELISA; Water Maze; Open Field; Biological Research on Drug Dependence; Biologisk beroendeforskning;

    Abstract : Drug dependence is a serious and increasing problem in our society, especially among adolescents. The use of the large variety of substances available can result in a range of physiological and psychological adverse effects on individuals and negative consequences on the society overall. READ MORE

  6. 4. Tolerance and antagonism to allopregnanolone effects in the rat CNS

    Author : Sahruh Turkmen; Inga-Maj Johansson; Agneta Nordberg; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Allopregnanolone; GABA-A receptor; UC1011; Spatial memory; Morris Water Maze; Tolerance; Silent second; mRNA; Obstetrics and gynaecology; Obstetrik och gynekologi;

    Abstract : Many studies have suggested a relationship between sex steroids and negative mental and mood changes in women. Allopregnanolone, a potent endogenous ligand of the GABA-A receptor and a metabolite of progesterone, is one of the most accused neuroactive steroids. READ MORE

  7. 5. Neuroactive steroids and rat CNS

    Author : Vita Birzniece; Bo Söderpalm; Umeå universitet; []
    Keywords : Estradiol; progesterone; HRT; allopregnanolone; UC1011; serotonin receptor; GABAA receptor; mRNA; Morris water maze; silent second; tolerance; Clinical Neurophysiology; klinisk neurofysiologi;

    Abstract : Several studies suggest profound effects on mood and cognition by neuroactive steroids. Estrogen alone or in combination with antidepressant drugs affecting the serotonin system has been used to treat mood disorders. On the other hand, progesterone is related to negative effects on mood and memory. READ MORE