Search for dissertations about: "What is next generation sequencing"

Showing result 1 - 5 of 7 swedish dissertations containing the words What is next generation sequencing.

2. 1. Prognostic and Predictive Somatic Mutations in Colorectal Cancer

   Author : Luís Nunes; Tobias Sjöblom; Bengt Glimelius; Snehangshu Kundu; Ivaylo Stoimenov; Laura DeLong Wood; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer; somatic mutations; next-generation sequencing; whole-genome sequencing; transcriptomics; targeted therapy; prognosis; Medicinsk vetenskap; Medical Science;

   Abstract : Colorectal cancer (CRC) is the third most incident and the second deadliest cancer worldwide. Even though CRC incidence is strongly correlated with age, it has been increasing in developing countries and younger individuals. READ MORE

4. 2. Full circle : Rise and fate of genetic variation in Marasmius oreades fairy rings

   Author : Markus Hiltunen; Hanna Johannesson; Martin Ryberg; Jason Stajich; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; mushroom; fairy ring; Marasmius; mutation; fungi; genomics; Biology with specialization in Systematics; Biologi med inriktning mot systematik;

   Abstract : Genetic variation is a prerequisite for evolution. The degree of variability within a species is governed by forces including mutation, recombination and selection. READ MORE

5. 3. Minimally Invasive Catheter-Based Technologies

   Author : Mikael Sandell; Göran Stemme; Staffan Holmin; Niclas Roxhed; Wouter van der Wijngaart; Stefan Jonsson; Duncan Maitland; KTH; Karolinska Institutet; Karolinska Institutet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicinsk teknologi; Medical Technology;

   Abstract : A simple incision procedure in a blood vessel makes the entire vascular system accessible. Through contrast injection and X-ray visualization, the vascular tree can be mapped and navigated through manual manipulation of thin tubes and wires. READ MORE

6. 4. Metaproteogenomics-guided enzyme discovery : Targeted identification of novel proteases in microbial communities

   Author : Mikaela Johansson; Martin Karlsson; Bengt-Harald Jonsson; Florian-Alexander Herbst; Linköpings universitet; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

   Abstract : Industrial biotechnology is a large and growing industry as it is part of establishing a “greener” and more sustainable bioeconomy-based society. Using enzymes as biocatalysts is a viable alternative to chemicals and energy intense industrial processes and is en route to a more sustainable industry. READ MORE

7. 5. Single-stranded DNA : methods and application in nanotechnology

   Author : Giulio Bernardinelli; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Basic molecular and cell research, production of recombinant proteins, diagnostic detection of genetic mutations, construction of nanostructures and high-throughput DNA sequencing are only a few examples of the diverse set of applications that are amenable thanks to the availability of synthetic DNA polymers in biomedicine. Strategic investments and technical progress together with the introduction of automation in the synthesis of DNA oligomers enabled to transform, in just a few decades, a process mastered only by a niche of biochemists into an affordable and available custom-made product to every scientific field. READ MORE