Search for dissertations about: "White blood cells"

Showing result 1 - 5 of 89 swedish dissertations containing the words White blood cells.

  1. 1. Acoustofluidic preparation of whole blood components

    Author : Anke Urbansky; NanoLund; []
    Keywords : acoustophoresis; ultrasound; microfluidics; cell separation; blood; blood fractionation;

    Abstract : Whole blood is rich in information about the physical state of an individual and is routinely used in a variety of clinical and research applications. In this thesis, the use of a microfluidic technique called acoustophoresis for separation of different blood components is explored. READ MORE

  2. 2. Regulation of the ribosomal RNA transcription by c-MYC oncoprotein

    Author : Azadeh Arabi; Anthony Wright; Robert White; Södertörns högskola; Karolinska Institutet; Karolinska Institutet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Myc; Nucleolus; Proteasome; RNA Polymerase; Cancer;

    Abstract : The transcription factor c-Myc is a key regulator of growth and proliferation. c-Myc levels are tightly controlled and deregulated c-Myc is often associated with human cancers. In our initial studies we observed that upon inhibition of proteasomes, excess c-Myc accumulates primarily in the nucleoli. READ MORE

  3. 3. Inflammatory Response in Peripheral Arterial Disease

    Author : Peter Danielsson; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; muskelsystem; reumatologi; rheumatology locomotion; Skelett; Skeleton; Polymorphism; Metabolism; Prostacyclin; Microdislysis; Diabetes mellitus; Revascularisation; Angioplasty; Endothelial cells; White blood cells; Inflammation; Peripheral Arterial Disease; muscle system;

    Abstract : Peripheral arterial disease (PAD) is the manifestation of atherosclerotic lesions in arteries supplying blood to the legs. Atherosclerosis is now recognized as an inflammatory disease of the vessel wall and important features in the pathophysiology are activation of WBC, endothelial cells and increased levels of inflammatory mediators. READ MORE

  4. 4. Biomarkers in sepsis and other severe infections

    Author : Helena Janols; Enheten för infektionssjukdomar; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunosuppression; myeloid-derived suppressor cells; T cells; dendritic cells; monocytes; sepsis; Biomarkers;

    Abstract : Infectious diseases constitute a major global health problem. The presenting clinical picture results from a mixture of direct toxic actions by the microbiological agent and of the immune response mounted by the host. READ MORE

  5. 5. Human truncated thioredoxin (Trx80) as a novel mitogenic cytokine for white blood cells

    Author : Klas Pekkari; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Abstract : Thioredoxin (Trx) is a 12 kDa protein present in all species with a well-conserved active site sequence comprising -Cys-Gly-Pro-Cys-, which catalyzes oxido-reductase reactions. Trx regulates the activity of transcription factors and intracellular signalling pathways, and secreted Trx is a co-cytokine with several interleukins. READ MORE