Search for dissertations about: "William S. Webster"

Found 1 swedish dissertation containing the words William S. Webster.

2. 1. Assessment of Drug-Induced Cardiotoxicity during Rat Embryo Development

   Author : Mats Nilsson; William S. Webster; Nigel A. Brown; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : The potassium ion channel (hERG/IKr) is important for normal heart function and drug-induced blockade of the channel in adult humans can lead to irregular heart rhythms (arrhythmia).  The ion channel is also essential for early cardiac function in the embryo and therapeutic drugs which block this channel have been shown to cause birth defects in animal studies. READ MORE