Search for dissertations about: "Wnt signaling"

Showing result 16 - 20 of 92 swedish dissertations containing the words Wnt signaling.

  2. 16. Wnt signaling affects cell adhesion and neuronal differentiation

    Author : Maria Lindqvist; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The mammalian central nervous system (CNS) consists of the brain and the spinal cord. The entire CNS is derived from the walls of a fluid-filled neural tube that is formed at an early stage of embryonic development. The tube itself becomes the adult ventricular system. READ MORE

  4. 17. Tumor progression in the ovary and colon. The interaction of Wnt-signaling, transcription and formation of prostaglandins

    Author : Katarina Rask; Göteborgs universitet; []
    Keywords : CCAAT Enhancer Binding Proteins C EBPs ; Wingless Wnt Wnt signaling pathway; Cyclooxygenases COXs ; colorectal cancer CRC ; epithelial ovarian cancer EOC ;

    Abstract : Alterations in cell-cell adhesion, intracellular signaling and transcriptional regulation are common events during transformation of cells to the malignant phenotype. Different cellular defense mechanisms, e.g. inflammatory responses, mediated by prostaglandins, have also been associated with tumor development. READ MORE

  5. 18. WNT/Frizzled signaling : illuminating the road towards pathway selectivity

    Author : Carl-Fredrik Bowin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cells sense and respond to their environment via receptors embedded in the plasma membrane. Receptors allow flow of information from outside to the inside of the cell and are generally regulated by extracellular molecules and proteins, known as ligands. READ MORE

  6. 19. Heparan sulfate dependent cell signaling and associated pathophysiology : Implications in tumorigenesis and embryogenesis

    Author : Tahira Batool; Jin-Ping Li; Aristidis Moustakas; Liliana Schaefer; Ingvar Ferby; Michael Welsh; Anders Malmström; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heparanase; Glucuronyl-C5 epimerase; Heparan Sulfate; Heparin; Lung Cancer; Cancer cell Singling; TGF-Beta; BMP; VEGF; Notch Signaling; Tumor growth; Metastasis; embryonic development; Medical Biochemistry; Medicinsk biokemi;

    Abstract : Heparan sulfate proteoglycans (HSPGs) consist of a protein core to which several linear, negatively charged heparan sulfate (HS) chains are covalently attached. HSPGs are expressed on the cell surface and in the extra-cellular matrix (ECM) where they have diverse biological functions, for example co-receptor functions. READ MORE

  7. 20. Wnt5a signaling in Malignant Melanoma

    Author : Elin Ekström; Malmö Experimentell patologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The Wnt signaling pathway is highly conserved and crucial during embryonic development. Aberrant Wnt signaling is important in several different disease processes. One such disease process is the development and progression of cancer. Malignant melanoma is a highly aggressive tumor type, in which Wnt signaling is essential. READ MORE