Search for dissertations about: "X chromosome population"

Showing result 1 - 5 of 36 swedish dissertations containing the words X chromosome population.

  2. 1. Population genetic history and patterns of admixture : Examples from northeastern and southern Africa

    Author : Nina Hollfelder; Mattias Jakobsson; Michele Ramsay; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; population structure; genetic admixture; genomic variation; Africa; population genomics; lactase persistence; sex-biased admixture; human evolutionary genetics; Biology with specialization in Evolutionary Organismal Biology; Biologi med inriktning mot evolutionär organismbiologi;

    Abstract : The origin of humans lies in Africa, as has been shown by archaeology, paleontology and genetics. Here, we can find the largest genetic diversity and the deepest split among human populations. African genetic diversity has been shaped by a long and complex history. READ MORE

  4. 2. Evolutionary Studies of the Mammalian Y Chromosome

    Author : Linda Hellborg; Hans Ellegren; Terry Burke; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Y chromosome; field vole; cattle; selection; primer design; Genetik; Clinical genetics; Klinisk genetik;

    Abstract : Sex chromosomes are useful in elucidating the evolutionary factors affecting diversity and divergence. In particular, Y chromosome analyses may complement studies using mitochondrial DNA for inferring sex-specific population genetic processes. READ MORE

  5. 3. Hopeful monsters: The role of hybrids in adaptation : The impact of hybridisation and genetic diversity on adaptation to stressful and novel environments

    Author : Ciaran Gilchrist; Rike Stelkens; Christopher Wheat; Linda Laikre; Mathilde Cordellier; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Experimental evolution; Saccharomyces cerevisiae; population genetics; hybridisation; adaptation; aneuploidy; comparative genomics; evolve-and-resequence; de novo mutations; evolutionary parallelism; populationsgenetik; Population Genetics;

    Abstract : Adaptation to novel environments can only occur if natural selection has the raw material to act upon. But small, endangered populations are often genetically depleted, and the acquisition of beneficial de novo mutations often takes too long when population face quick and extreme environmental change. READ MORE

  6. 4. Population-based prediction of atrial fibrillation

    Author : Gustav Smith; Kardiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atrial fibrillation; prediction; epidemiology; genetics; natriuretic peptide; heart failure;

    Abstract : Background: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and increases in prevalence. As AF confers increased risk of morbidity, stroke, dementia and mortality, a major objective of cardiovascular epidemiology today is the development of tools for prediction and prevention of AF and its consequences. READ MORE

  7. 5. Cytogenetic abnormalities in Acute Myeloid Leukemia in Sweden. A population based study

    Author : Vladimir Lazarevic; Stamcellscentrum (SCC); []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; AML; karyotype; population-based studies; prognosis; chromosomes; hyperdiploidy;

    Abstract : The impact of cytogenetic findings in AML was analyzed in the large population-based Swedish AML registry. Karyotypic patterns differed by age: t(8;21), inv(16) and t(11q23) were more common in younger patients, whereas loss of 5q, 7q and 17p, monosomal karyotype (MK) and complex karyotype (CK) were more common in older patients. READ MORE