Search for dissertations about: "XAP-2"

Found 3 swedish dissertations containing the word XAP-2.

2. 1. Regulation of transcription factors by XAP-2 : a member of the Hsp90 chaperone complex

   Author : Petra Berg; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The AhR belongs to the bHLH/PAS family of transcription factors, which mediates biological effects of environmental pollutants such as 2,3,7,8-tetrachlorodibenzo-rho-dioxin (TCDD). In the absence of ligand the AhR is located in the cytoplasmatic compartment of the cell associated with the molecular chaperone Hsp90, p23 and a member of the immunophilin family of proteins, XAP-2. READ MORE

4. 2. Regulation of gene transcription by the thyroid hormone receptors

   Author : Maria Nygård; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Thyroid hormone receptors; T3; cell differentiation; gene regulation; E2F-1; Necdin; TRH; nTRE; RXR; NCoR; XAP-2;

   Abstract : Thyroid hormone (TH) has important effects on postnatal development as well as on adult metabolic homeostasis. TH meditates its effects through different isoforms of the thyroid hormone receptors (TRs) encoded by the TRalpha and TRbeta genes, respectively. TRs belong to the nuclear hormone receptor superfamily. READ MORE

5. 3. Identification of EBNA binding cellular proteins, using yeast two-hybrid system

   Author : Elena Kashuba; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Epstein-Barr virus (EBV) is a common herpesvirus that establishes life-long persistence in the human host through the elaborate regulation of different latency types. Latent EBV infection of resting B cells converts them into transformed cells that can develop into tumors in immune-compromised hosts. READ MORE