Advanced search

Showing result 1 - 5 of 32 swedish dissertations matching the above criteria.

  2. 1. Molecular aspects on voltage-sensor movement

    Author : Amir Broomand; Fredrik Elinder; Guiscard Seebohm; Linköpings universitet; []
    Keywords : Potassium channels; voltage-gated; chemistry; metabolism; physiology; patch-clamp techniques; oocytes; MEDICINE; MEDICIN;

    Abstract : Voltage-gated ion channels are fundamental for electrical signaling in living cells. They are composed of four subunits, each holding six transmembrane helices, S1-S6. Each subunit contains a voltage-sensor domain, S1-S4, and a pore domain, S5-S6. READ MORE

  4. 2. Developmental and Reproductive Toxicity of Progestagens in the Xenopus (Silurana) tropicalis Test System

    Author : Moa Säfholm; Cecilia Berg; Ingvar Brandt; Jan Olsson; Louis Guillette; Uppsala universitet; []
    Keywords : Xenopus tropicalis; sex organ differentiation; oogenesis; fertility; ovary; oviduct; progestagens; Biologi med inriktning mot ekotoxikologi; Biology with specialization in Environmental Toxicology;

    Abstract : Progestagenic compounds are emerging contaminants found in surface and ground water around the world. Information on the effects and potency of progestagens is needed in order to understand the environmental risks posed by these compounds. READ MORE

  5. 3. The role of ion channels and intracellular metal ions in apoptosis of Xenopus oocytes

    Author : Ulrika Englund; Fredrik Elinder; Johan Brask; Katarina Kågedal; Dan Klaerke; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Apoptosis is one type of programmed cell death, important during tissue development and to maintain the tissue homeostasis. Apoptosis comprises a complex network of internal signaling pathways, and an important part of this signaling network is the action of voltage‐gated ion channels. READ MORE

  6. 4. Zinc Oxide Nanostructure Based Electrochemical Sensors and Drug Delivery to Intracellular Environments

    Author : Muhammad Asif; Magnus Willander; Omer Nour; Sunil Bhand; Linköpings universitet; []
    Keywords : ZnO nanorods; Intracellular electrochemical sensor; Functionalization; Metal ions; Glucose; Human Adipocytes; Frog Oocytes; Airway surface liquid; NATURAL SCIENCES; NATURVETENSKAP;

    Abstract : The nanoscale science and nanostructure engineering have well established in the fabrication of novel electrochemical biosensors with faster response and higher sensitivity than of planar sensor configurations. Moreover nanostructures are suggested and used as efficient carrier of photosensitizers for cancerous cell treatment. READ MORE

  7. 5. Effects of neuroactive steroids on the recombinant GABAA receptor in Xenopus oocyte

    Author : Mozibur Rahman; Ming-De Wang; Bjarke Ebert; Umeå universitet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; GABA; GABAA receptor; neuroactive steroids; Obstetrics and gynaecology; Obstetrik och gynekologi;

    Abstract : Introduction: Neuroactive steroids represent a class of both synthetic and naturally occurring steroids that have an effect on neural function. In addition to classical genomic mechanism by the hormones progesterone, deoxycorticosterone and testosterone 3α-OH metabolites of these hormones enhance GABAA receptor through rapid non-genomic mechanism. READ MORE