Search for dissertations about: "Xenopus tropicalis"

Showing result 1 - 5 of 7 swedish dissertations containing the words Xenopus tropicalis.

  2. 1. The Xenopus tropicalis model for developmental endocrine and reproductive toxicity : Histological and molecular endpoints for disrupted spermatogenesis

    Author : Sofie Svanholm; Cecilia Berg; Oskar Karlsson; Valérie Langlois; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Endocrine disrupting chemicals; Reproductive toxicology; Developmental toxicology; Spermatogenesis; Transgenerational; Xenopus tropicalis; Biology with specialization in Environmental Toxicology; Biologi med inriktning mot miljötoxikologi;

    Abstract : Endocrine disrupting chemicals (EDCs) are linked to adverse effects in both humans and wildlife. There are however, large knowledge gaps regarding cause-effect and dose-response relationships between the interference with endocrine pathways and adverse effects in the organism, especially at puberty and in subsequent generations. READ MORE

  4. 2. Developmental and Reproductive Toxicity of Progestagens in the Xenopus (Silurana) tropicalis Test System

    Author : Moa Säfholm; Cecilia Berg; Ingvar Brandt; Jan Olsson; Louis Guillette; Uppsala universitet; []
    Keywords : Xenopus tropicalis; sex organ differentiation; oogenesis; fertility; ovary; oviduct; progestagens; Biologi med inriktning mot ekotoxikologi; Biology with specialization in Environmental Toxicology;

    Abstract : Progestagenic compounds are emerging contaminants found in surface and ground water around the world. Information on the effects and potency of progestagens is needed in order to understand the environmental risks posed by these compounds. READ MORE

  5. 3. Ontogenetic Characterization of Müllerian Duct Development and Expression of anti-Müllerian hormone and Other Genes : New Endpoints in the Frog Xenopus tropicalis Test System

    Author : Erika Jansson; Cecilia Berg; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : The amphibian model-species Xenopus tropicalis is used in reproductive toxicology studies. Lifecycle studies are requested but they are time consuming and susceptible to several of the risks attributed to long-term studies. READ MORE

  6. 4. Endocrine Disruption in Amphibians : Developmental Effects of Ethynylestradiol and Clotrimazole on the Reproductive System

    Author : Irina Gyllenhammar; Cecilia Berg; Ingvar Brandt; Lena Holm; Joakim Larsson; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Test system; Xenopus tropicalis; Rana temporaria; sex ratio; sex differentiation; fertility; aromatase; ovary; testis; oviduct; Biology; Biologi;

    Abstract : Amphibian populations are declining world-wide and one of the suggested reasons is environmental pollutants. Studies of long-term effects on the reproductive system in frogs following larval exposure to environmental pollutants are scarce. It is therefore important to develop methods to study developmental reproductive toxicity in amphibians. READ MORE

  7. 5. The role of ion channels and intracellular metal ions in apoptosis of Xenopus oocytes

    Author : Ulrika Englund; Fredrik Elinder; Johan Brask; Katarina Kågedal; Dan Klaerke; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Apoptosis is one type of programmed cell death, important during tissue development and to maintain the tissue homeostasis. Apoptosis comprises a complex network of internal signaling pathways, and an important part of this signaling network is the action of voltage‐gated ion channels. READ MORE