Search for dissertations about: "YOYO-1"

Showing result 1 - 5 of 6 swedish dissertations containing the word YOYO-1.

  2. 1. Amyloid Fibril Formation - Dye Detection and Effects of Lipids

    Author : David Lindberg; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atomic force microscopy; fluorescence; Alzheimer’s disease; YOYO-1; amyloid fibrils; lipids; linear dichroism; FRET; circular dichroism; kinetics; Protein aggregation; insulin; thioflavin-T;

    Abstract : Amyloid fibrils are long fibrillar homopolymers of self-assembled proteins. They can be formed by essentially any polypeptide, but are of particular interest because of their occurrence in several incurable and debilitating human diseases, e.g. Alzheimer’s disease (AD). READ MORE

  4. 2. Development of the Amyloid Fibril Characterisation Toolbox - New use for old dyes

    Author : David Lindberg; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Amyloid-β; Thioflavin-T; Fluorescence spectroscopy; YOYO-1; Amyloid fibrils; Linear dichroism; Alzheimer’s disease;

    Abstract : Amyloid fibrils are self-assembled protein homopolymers that playcentral roles in the pathology of several human diseases, most notably in progressiveneurodegenerative diseases such as Alzheimer’s disease (AD). In AD, fibrils areformed by the amyloid-β (Aβ) peptide, an enzymatic cleavage product that is naturallyproduced in human brain tissue. READ MORE

  5. 3. Development of methods for optical mapping of nanoconfined DNA

    Author : Lena Nyberg; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; competitive binding; optical mapping; YOYO-1; nanofluidics; antibiotic resistance; fluorescence microscopy; single-molecule; DNA; plasmids; netropsin;

    Abstract : .... READ MORE

  6. 4. Development of Methods for Single-Molecule Studies of DNA in Nanofluidic Channels

    Author : Lena Nyberg; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; fluorescence microscopy; YOYO-1; Nanofluidics; netropsin; competitive binding; DNA; single-molecule;

    Abstract : .... READ MORE

  7. 5. Competitive-Binding Based Optical DNA Mapping - From Bacterial Plasmids to the Human Genome

    Author : Vilhelm Müller; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; genetics; single-molecule; nanofluidics; DNA; antibiotic resistance; optical DNA mapping; plasmids; competitive binding; fluorescence microscopy; bacteria;

    Abstract : Significant advances within the field of DNA sequencing have allowed us to study DNA at a level of detail that was previously impossible. However, dynamic genomic regions with a high degree of structural variations, while being linked to disease in humans and increased resistance to antibiotics, are still challenging to characterize. READ MORE