Search for dissertations about: "Yersinia pestis"

Showing result 1 - 5 of 11 swedish dissertations containing the words Yersinia pestis.

  2. 1. Outer membrane proteins of Yersinia pestis : Ail and OmpA

    Author : Sara Celinda Schesser Bartra; Hans Wolf-Watz; Virginia Miller; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Yersinia pestis; outer membrane proteins; Ail; ompA; Microbiology; immunology; infectious diseases; Mikrobiologi; immunologi; infektionssjukdomar; immunologi; Immunology; mikrobiologi; Microbiology; Infectious Diseases; infektionssjukdomar;

    Abstract : A vast number of studies have been completed on the virulence determinants of Yersinia spp.; however, the focus of many of these studies has been on the virulence plasmid and the plasmid-encoded Type three secretion system. Nevertheless, many chromosomal genes whose products are directly involved in virulence have also been identified. READ MORE

  4. 2. Virulence mechanisms of pathogenic Yersinia : aspects of type III secretion and twin arginine translocation

    Author : Moa Lavander; Åke Forsberg; George Salmond; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Yersinia pestis; Yersinia pseudotuberculosis; bacterial pathogenesis; type III secretion; twin arginine translocation; virulence mechanisms; YscU; YscP; YscF; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Abstract : The pathogenic bacteria Yersinia pestis and Y. pseudotuberculosis are related to the degree where the former is considered a subspecies of the latter, and still they cause disease of little resemblance in humans. Y. pestis is the causative agent of lethal bubonic and pneumonic plague, while Y. READ MORE

  5. 3. Yersinia-phagocyte interactions during early infection

    Author : Linda Westermark; Maria Fällman; Joan Mecsas; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Yersinia; dendritic cell; macrophage; neutrophil; T3SS; Infectious Diseases; infektionssjukdomar;

    Abstract : Pathogenic Gram-negative Yersinia species preferentially target and inactivate phagocytic cells of the innate immune defense by translocation of effector Yersinia outer proteins (Yops) into the cells via a type III secretion system. This indicates that inactivation and avoidance of the early innate immune response is an efficient way for Yersinia species to avoid elimination and to cause diseases ranging from mild gastroenteritis (Y. READ MORE

  6. 4. Role of the Yersinia protein YopK in microbe-host interactions

    Author : Sara Thorslund; Maria Fällman; James Bliska; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Yersinia; YopK; T3SS; antiphagocytosis; neutrophil; translocation; virulence; molekylärbiologi; Molecular Biology;

    Abstract : There are three human pathogenic species of the genus Yersiniae: Yersinia pestis, Yersinia enterocolitica, and Yersinia pseudotuberculosis. To cause disease, these strains inhibit several key innate defense mechanisms, including phagocytosis, the critical process for bacterial clearance. READ MORE

  7. 5. Twin-arginine translocation in Yersinia : the substrates and their role in virulence

    Author : Ummehan Avican; Åke Forsberg; Åsa Sjöling; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Yersinia pseudotuberculosis; Tat; virulence; Tat substrates; SufI; stress response; metabolism; infection; transcriptome analysis; Infectious Diseases; infektionssjukdomar; molekylärbiologi; Molecular Biology; mikrobiologi; Microbiology;

    Abstract : Pathogenic Yersinia cause a manifold of diseases in humans ranging from mild gastroenteritis (Y. pseudotuberculosis and Y. enterocolitica) to pneumonic and bubonic plague (Y. READ MORE