Search for dissertations about: "Yersinia"

Showing result 1 - 5 of 55 swedish dissertations containing the word Yersinia.

  1. 1. Virulence mechanisms of pathogenic Yersinia aspects of type III secretion and twin arginine translocation

    University dissertation from Umeå : Molekylärbiologi (Teknisk-naturvetenskaplig fakultet)

    Author : Moa Lavander; Åke Forsberg; George Salmond; [2005]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Yersinia pestis; Yersinia pseudotuberculosis; bacterial pathogenesis; type III secretion; twin arginine translocation; virulence mechanisms; YscU; YscP; YscF; Molekylärbiologi; NATURAL SCIENCES Biology Cell and molecular biology Molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Abstract : The pathogenic bacteria Yersinia pestis and Y. pseudotuberculosis are related to the degree where the former is considered a subspecies of the latter, and still they cause disease of little resemblance in humans. Y. pestis is the causative agent of lethal bubonic and pneumonic plague, while Y. READ MORE

  2. 2. Persistent infection by Yersinia pseudotuberculosis

    University dissertation from Umeå : Umeå University

    Author : Kemal Avican; Maria Fällman; Wyndham W. Lathem; [2015]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Persistent infection; RNA-seq; PMNs; Yersinia; Transcriptome; wrba; fnr; rovA; arcA; rfaH; molekylärbiologi; Molecular Biology; Infectious Diseases; infektionssjukdomar; immunologi; Immunology;

    Abstract : Enteropathogenic Yersinia species can infect many mammalian organs such as the small intestine, cecum, Peyer’s patches, liver, spleen, and lung and cause diseases that resemble a typhoid-like syndrome, as seen for other enteropathogens. We found that sublethal infection doses of Y. READ MORE

  3. 3. Yersinia-phagocyte interactions during early infection

    University dissertation from Umeå : Umeå University

    Author : Linda Westermark; Maria Fällman; Joan Mecsas; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Yersinia; dendritic cell; macrophage; neutrophil; T3SS; Infectious Diseases; infektionssjukdomar;

    Abstract : Pathogenic Gram-negative Yersinia species preferentially target and inactivate phagocytic cells of the innate immune defense by translocation of effector Yersinia outer proteins (Yops) into the cells via a type III secretion system. This indicates that inactivation and avoidance of the early innate immune response is an efficient way for Yersinia species to avoid elimination and to cause diseases ranging from mild gastroenteritis (Y. READ MORE

  4. 4. Delivery of TypeIII Secreted Toxins by Yersinia pseudotuberculosis the Role of LcrV, YopD, and Free Lipids in the Translocation Process

    University dissertation from Umeå : Molekylärbiologi (Teknisk-naturvetenskaplig fakultet)

    Author : Jan Olsson; Hans Wolf-Watz; Ina Attree; [2006]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Yersinia; T3SS; translocation; YopD; LcrV; YLC; fatty acids.; NATURAL SCIENCES Chemistry Biochemistry Molecular biology; NATURVETENSKAP Kemi Biokemi Molekylärbiologi;

    Abstract : Bacteria that infect humans and animals face a hard combat with the host´s immune system and in order to establish infection, pathogenic bacteria has evolved mechanisms to avoid being cleared from the host tissue. Many Gram-negatives carry a Type 3 secretion (T3S) system that is used to deliver effector proteins (toxins) into host cells. READ MORE

  5. 5. Twin-arginine translocation in Yersinia the substrates and their role in virulence

    University dissertation from Umeå : Umeå University

    Author : Ummehan Avican; Åke Forsberg; Åsa Sjöling; [2016]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Yersinia pseudotuberculosis; Tat; virulence; Tat substrates; SufI; stress response; metabolism; infection; transcriptome analysis; Infectious Diseases; infektionssjukdomar; molekylärbiologi; Molecular Biology; mikrobiologi; Microbiology;

    Abstract : Pathogenic Yersinia cause a manifold of diseases in humans ranging from mild gastroenteritis (Y. pseudotuberculosis and Y. enterocolitica) to pneumonic and bubonic plague (Y. READ MORE